Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
3R01EY000260-22S1
Application #
3255228
Study Section
Vision Research and Training Committee (VSN)
Project Start
1979-09-01
Project End
1988-08-31
Budget Start
1984-09-01
Budget End
1985-08-31
Support Year
22
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Emory University
Department
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Kuck, J F (1990) Late onset hereditary cataract of the emory mouse. A model for human senile cataract. Exp Eye Res 50:659-64
Lo, W K; Kuck, J F (1990) Alterations of urea-insoluble membrane fraction, MP26, of Emory mouse lenses in aging and cataractogenesis. Ophthalmic Res 22:82-8
Cai, M Z; Kuck Jr, J F; Yu, N T (1989) Galactose-induced cataract in rat: Raman detection of sulfhydryl decrease and water increase along an equatorial diameter. Exp Eye Res 49:531-41
Kuck, J F; Kuck, K D (1989) The Emory mouse cataract: increased accumulation of calcium during cataractogenesis. Lens Eye Toxic Res 6:853-62
Reddan, J R; Kuck, J F; Dziedzic, D C et al. (1989) Establishment of lens epithelial cell lines from Emory and cataract resistant mice and their response to hydrogen peroxide. Lens Eye Toxic Res 6:687-701
Yu, N T; Barron, B C; Kuck Jr, J F (1989) Distribution of two metabolically related fluorophors in human lens measured by laser microprobe. Exp Eye Res 49:189-94
DeNagel, D C; Bando, M; Yu, N T et al. (1988) A Raman study of disulfide and sulfhydryl in the Emory mouse cataract. Invest Ophthalmol Vis Sci 29:823-6
Yu, N T; Cai, M Z; Ho, D J et al. (1988) Automated laser-scanning-microbeam fluorescence/Raman image analysis of human lens with multichannel detection: evidence for metabolic production of a green fluorophor. Proc Natl Acad Sci U S A 85:103-6
Barron, B C; Yu, N T; Kuck Jr, J F (1988) Raman spectroscopic evaluation of aging and long-wave UV exposure in the guinea pig lens: a possible model for human aging. Exp Eye Res 46:249-58
Kuck Jr, J F; Kuck, K D (1988) The Emory mouse cataract: the effects on cataractogenesis of alpha-tocopherol, penicillamine, triethylenetetramine, and mercaptopropionylglycine. J Ocul Pharmacol 4:243-51

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