PROPOSED WORK: a) Development of a processing system for continuous measurements of the speed of red blood cells in retinal vessels and in the microcirculation of the optic nerve and choroid. b) Study of retinal, choroidal and optic nerve autoregulation in response to changes in intraocular pressure. Determination of the time course of the autoregulation response and of the maximal intraocular pressure at which autoregulation is fully effective. c) Study of the penetration of laser light into the optic nerve tissue. d) Investigation of fluorescein diffusion into the optic nerve of patients with ocular hypertension and glaucoma.
| Riva, C E; Cranstoun, S D; Petrig, B L (1996) Effect of decreased ocular perfusion pressure on blood flow and the flicker-induced flow response in the cat optic nerve head. Microvasc Res 52:258-69 |
| Grunwald, J E; DuPont, J; Riva, C E (1996) Retinal haemodynamics in patients with early diabetes mellitus. Br J Ophthalmol 80:327-31 |
| Mann, R M; Riva, C E; Stone, R A et al. (1995) Nitric oxide and choroidal blood flow regulation. Invest Ophthalmol Vis Sci 36:925-30 |
| Vo Van Toi; Riva, C E (1995) Variations of blood flow at optic nerve head induced by sinusoidal flicker stimulation in cats. J Physiol 482 ( Pt 1):189-202 |
| Portellos, M; Riva, C E; Cranstoun, S D et al. (1995) Effects of adenosine on ocular blood flow. Invest Ophthalmol Vis Sci 36:1904-9 |
| Riva, C E; Cranstoun, S D; Mann, R M et al. (1994) Local choroidal blood flow in the cat by laser Doppler flowmetry. Invest Ophthalmol Vis Sci 35:608-18 |
| Scheiner, A J; Riva, C E; Kazahaya, K et al. (1994) Effect of flicker on macular blood flow assessed by the blue field simulation technique. Invest Ophthalmol Vis Sci 35:3436-41 |
| Riva, C E; Cranstoun, S D; Grunwald, J E et al. (1994) Choroidal blood flow in the foveal region of the human ocular fundus. Invest Ophthalmol Vis Sci 35:4273-81 |
| Grunwald, J E; Brucker, A J; Grunwald, S E et al. (1993) Retinal hemodynamics in proliferative diabetic retinopathy. A laser Doppler velocimetry study. Invest Ophthalmol Vis Sci 34:66-71 |
| Pakola, S J; Grunwald, J E (1993) Effects of oxygen and carbon dioxide on human retinal circulation. Invest Ophthalmol Vis Sci 34:2866-70 |
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