Abstract

The objectives of this study are to document and describe alterations in the appearance of the retinal nerve fiber layer that accompany glaucomatous visual field loss; and to determine the reliability and value of such changes, alone and in combination with the appearance of a variety of disc parameters, as a means of identifying individuals already having visual field loss, and predicting which ocular hypertensives will eventually develop field loss. Normal controls, ocular hypertensives, and patients with established glaucomatous field loss will be followed prospectively, repeatedly examined, and their disc and nerve fiber layer photographed. These photographs will be read in masked, randomized, controlled fashion and the sensitivity and specificity of the test, in temporal relationship to the eventual onset of glaucomatous field loss, determined.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY003605-05
Application #
3257988
Study Section
(VID)
Project Start
1981-09-01
Project End
1986-09-29
Budget Start
1985-09-01
Budget End
1986-09-29
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Katz, J (2000) A comparison of the pattern- and total deviation-based Glaucoma Change Probability programs. Invest Ophthalmol Vis Sci 41:1012-6
Katz, J; Congdon, N; Friedman, D S (1999) Methodological variations in estimating apparent progressive visual field loss in clinical trials of glaucoma treatment. Arch Ophthalmol 117:1137-42
Katz, J (1999) Scoring systems for measuring progression of visual field loss in clinical trials of glaucoma treatment. Ophthalmology 106:391-5
Friedman, D S; Katz, J; Bressler, N M et al. (1999) Racial differences in the prevalence of age-related macular degeneration: the Baltimore Eye Survey. Ophthalmology 106:1049-55
Lietman, T; Eng, J; Katz, J et al. (1999) Neural networks for visual field analysis: how do they compare with other algorithms? J Glaucoma 8:77-80
Katz, J; Gilbert, D; Quigley, H A et al. (1997) Estimating progression of visual field loss in glaucoma. Ophthalmology 104:1017-25
Katz, J; Quigley, H A; Sommer, A (1996) Detection of incident field loss using the glaucoma hemifield test. Ophthalmology 103:657-63
Katz, J; Quigley, H A; Sommer, A (1995) Repeatability of the Glaucoma Hemifield Test in automated perimetry. Invest Ophthalmol Vis Sci 36:1658-64
Katz, J; Tielsch, J M; Quigley, H A et al. (1995) Automated perimetry detects visual field loss before manual Goldmann perimetry. Ophthalmology 102:21-6
Quigley, H A; Enger, C; Katz, J et al. (1994) Risk factors for the development of glaucomatous visual field loss in ocular hypertension. Arch Ophthalmol 112:644-9

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