Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009033-04
Application #
2162638
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1992-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1997-11-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Demidova-Rice, Tatiana N; Geevarghese, Anita; Herman, Ira M (2011) Bioactive peptides derived from vascular endothelial cell extracellular matrices promote microvascular morphogenesis and wound healing in vitro. Wound Repair Regen 19:59-70
Durham, Jennifer T; Herman, Ira M (2009) Inhibition of angiogenesis in vitro: a central role for beta-actin dependent cytoskeletal remodeling. Microvasc Res 77:281-8
Kutcher, Matthew E; Herman, Ira M (2009) The pericyte: cellular regulator of microvascular blood flow. Microvasc Res 77:235-46
Herman, Ira M; Leung, Alice (2009) Creation of human skin equivalents for the in vitro study of angiogenesis in wound healing. Methods Mol Biol 467:241-8
Kutcher, Matthew E; Kolyada, Alexey Y; Surks, Howard K et al. (2007) Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state. Am J Pathol 171:693-701
Sieczkiewicz, Gregory J; Herman, Ira M (2003) TGF-beta 1 signaling controls retinal pericyte contractile protein expression. Microvasc Res 66:190-6
Potter, David A; Srirangam, Anjaiah; Fiacco, Kerry A et al. (2003) Calpain regulates enterocyte brush border actin assembly and pathogenic Escherichia coli-mediated effacement. J Biol Chem 278:30403-12
Papetti, Michael; Shujath, Jaleel; Riley, Kathleen N et al. (2003) FGF-2 antagonizes the TGF-beta1-mediated induction of pericyte alpha-smooth muscle actin expression: a role for myf-5 and Smad-mediated signaling pathways. Invest Ophthalmol Vis Sci 44:4994-5005
Kolyada, Alexey Y; Riley, Kathleen N; Herman, Ira M (2003) Rho GTPase signaling modulates cell shape and contractile phenotype in an isoactin-specific manner. Am J Physiol Cell Physiol 285:C1116-21
Riley, Kathleen N; Maldonado, Angel E; Tellier, Patrice et al. (2003) Betacap73-ARF6 interactions modulate cell shape and motility after injury in vitro. Mol Biol Cell 14:4155-61

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