Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009370-04
Application #
2162985
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1992-01-01
Project End
1996-12-31
Budget Start
1995-01-01
Budget End
1996-12-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Washington University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Chen, Q; Olney, J W; Lukasiewicz, P D et al. (1998) Ca2+-independent excitotoxic neurodegeneration in isolated retina, an intact neural net: a role for Cl- and inhibitory transmitters. Mol Pharmacol 53:564-72
Romano, C; Yang, W L; O'Malley, K L (1996) Metabotropic glutamate receptor 5 is a disulfide-linked dimer. J Biol Chem 271:28612-6
Sha, Q; Romano, C; Lopatin, A N et al. (1996) Spermidine release from xenopus oocytes. Electrodiffusion through a membrane channel. J Biol Chem 271:3392-7
Valentino, T L; Lukasiewicz, P D; Romano, C (1996) Immunocytochemical localization of polyamines in the tiger salamander retina. Brain Res 713:278-85
Godwin, D W; Van Horn, S C; Eriir, A et al. (1996) Ultrastructural localization suggests that retinal and cortical inputs access different metabotropic glutamate receptors in the lateral geniculate nucleus. J Neurosci 16:8181-92
Romano, C; van den Pol, A N; O'Malley, K L (1996) Enhanced early developmental expression of the metabotropic glutamate receptor mGluR5 in rat brain: protein, mRNA splice variants, and regional distribution. J Comp Neurol 367:403-12
Romano, C; Sesma, M A; McDonald, C T et al. (1995) Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. J Comp Neurol 355:455-69
Reid, S N; Romano, C; Hughes, T et al. (1995) Immunohistochemical study of two phosphoinositide-linked metabotropic glutamate receptors (mGluR1 alpha and mGluR5) in the cat visual cortex before, during, and after the peak of the critical period for eye-specific connections. J Comp Neurol 355:470-7
Romano, C; Price, M T; Olney, J W (1995) Delayed excitotoxic neurodegeneration induced by excitatory amino acid agonists in isolated retina. J Neurochem 65:59-67
Romano, C; Barrett, D A; Li, Z et al. (1995) Anti-rhodopsin antibodies in sera from patients with normal-pressure glaucoma. Invest Ophthalmol Vis Sci 36:1968-75

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