Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009631-04
Application #
2163307
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1991-08-01
Project End
1996-07-31
Budget Start
1994-08-01
Budget End
1995-07-31
Support Year
4
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Wayne State University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Yamazaki, Akio; Nishizawa, Yuji; Matsuura, Isao et al. (2013) Microtubule-associated protein tau in bovine retinal photoreceptor rod outer segments: comparison with brain tau. Biochim Biophys Acta 1832:1549-59
Yamazaki, Akio; Hayashi, Fumio; Matsuura, Isao et al. (2011) Binding of cGMP to the transducin-activated cGMP phosphodiesterase, PDE6, initiates a large conformational change involved in its deactivation. FEBS J 278:1854-72
Yamazaki, Akio; Tatsumi, Masahiro; Bondarenko, Vladimir A et al. (2010) Mechanism for the regulation of mammalian cGMP phosphodiesterase6. 2: isolation and characterization of the transducin-activated form. Mol Cell Biochem 339:235-51
Yamazaki, Akio; Bondarenko, Vladimir A; Matsuura, Isao et al. (2010) Mechanism for the regulation of mammalian cGMP phosphodiesterase6. 1: identification of its inhibitory subunit complexes and their roles. Mol Cell Biochem 339:215-33
Bondarenko, Vladimir A; Hayashi, Fumio; Usukura, Jiro et al. (2010) Involvement of rhodopsin and ATP in the activation of membranous guanylate cyclase in retinal photoreceptor outer segments (ROS-GC) by GC-activating proteins (GCAPs): a new model for ROS-GC activation and its link to retinal diseases. Mol Cell Biochem 334:125-39
Yamazaki, Akio; Yamazaki, Matsuyo; Yamazaki, Russell K et al. (2006) Illuminated rhodopsin is required for strong activation of retinal guanylate cyclase by guanylate cyclase-activating proteins. Biochemistry 45:1899-909
Yamazaki, Matsuyo; Usukura, Jiro; Yamazaki, Russell K et al. (2005) ATP binding is required for physiological activation of retinal guanylate cyclase. Biochem Biophys Res Commun 338:1291-8
Yamazaki, Akio; Yu, Hao; Yamazaki, Matsuyo et al. (2003) A critical role for ATP in the stimulation of retinal guanylyl cyclase by guanylyl cyclase-activating proteins. J Biol Chem 278:33150-60
Yamazaki, Akio; Moskvin, Oleg; Yamazaki, Russell K (2002) Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit (Pgamma) of retinal cgmp phosphodiesterase (PDE6): its implications in phototransduction. Adv Exp Med Biol 514:131-53
Yamazaki, Matsuyo; Li, Ning; Bondarenko, Vladimir A et al. (2002) Binding of cGMP to GAF domains in amphibian rod photoreceptor cGMP phosphodiesterase (PDE). Identification of GAF domains in PDE alphabeta subunits and distinct domains in the PDE gamma subunit involved in stimulation of cGMP binding to GAF domains. J Biol Chem 277:40675-86

Showing the most recent 10 out of 30 publications