Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009721-05
Application #
2163435
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1992-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Hay, Elizabeth D (2005) The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it. Dev Dyn 233:706-20
Kim, Kwonseop; Lu, Zifan; Hay, Elizabeth D (2002) Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT. Cell Biol Int 26:463-76
Kim, Kwonseop; Sirota, Anna; Chen Yh, Yan-hua et al. (2002) Dendrite-like process formation and cytoskeletal remodeling regulated by delta-catenin expression. Exp Cell Res 275:171-84
Kim, K; Hay, E D (2001) New evidence that nuclear import of endogenous beta-catenin is LEF-1 dependent, while LEF-1 independent import of exogenous beta-catenin leads to nuclear abnormalities. Cell Biol Int 25:1149-61
Kim, K; Pang, K M; Evans, M et al. (2000) Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators. Mol Biol Cell 11:3509-23
Hay, E D (1999) Biogenesis and organization of extracellular matrix. FASEB J 13 Suppl 2:S281-3
Kim, K; Daniels, K J; Hay, E D (1998) Tissue-specific expression of beta-catenin in normal mesenchyme and uveal melanomas and its effect on invasiveness. Exp Cell Res 245:79-90
Harkin, D G; Hay, E D (1996) Effects of electroporation on the tubulin cytoskeleton and directed migration of corneal fibroblasts cultured within collagen matrices. Cell Motil Cytoskeleton 35:345-57
Vanderburg, C R; Hay, E D (1996) E-cadherin transforms embryonic corneal fibroblasts to stratified epithelium with desmosomes. Acta Anat (Basel) 157:87-104
Hay, E D; Zuk, A (1995) Transformations between epithelium and mesenchyme: normal, pathological, and experimentally induced. Am J Kidney Dis 26:678-90

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