Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009730-03
Application #
2163446
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1994-08-01
Project End
1998-03-31
Budget Start
1996-08-01
Budget End
1998-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Jha, Purushottam; Sohn, Jeong-Hyeon; Xu, Qin et al. (2006) Suppression of complement regulatory proteins (CRPs) exacerbates experimental autoimmune anterior uveitis (EAAU). J Immunol 176:7221-31
Bora, Puran S; Sohn, Jeong-Hyeon; Cruz, Jose M C et al. (2005) Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization. J Immunol 174:491-7
Bora, Nalini S; Sohn, Jeong-Hyeon; Bora, Puran S et al. (2005) Anti-inflammatory effects of specific cyclooxygenase 2,5-lipoxygenase, and inducible nitric oxide synthase inhibitors on experimental autoimmune anterior uveitis (EAAU). Ocul Immunol Inflamm 13:183-9
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Sohn, Jeong-Hyeon; Bora, Puran S; Suk, Hye-Jung et al. (2003) Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells. Nat Med 9:206-12
McLaughlin, Barbara J; Fan, Wei; Zheng, Jing Juan et al. (2003) Novel role for a complement regulatory protein (CD46) in retinal pigment epithelial adhesion. Invest Ophthalmol Vis Sci 44:3669-74
Li, Jianjun; Hu, Weimin; Baldassare, Joseph J et al. (2003) The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci 73:1083-96
Oruc, S; Duffy, B F; Mohanakumar, T et al. (2001) The association of HLA class II with pars planitis. Am J Ophthalmol 131:657-9
Sohn, J H; Kaplan, H J; Suk, H J et al. (2000) Complement regulatory activity of normal human intraocular fluid is mediated by MCP, DAF, and CD59. Invest Ophthalmol Vis Sci 41:4195-202
Sohn, J H; Kaplan, H J; Suk, H J et al. (2000) Chronic low level complement activation within the eye is controlled by intraocular complement regulatory proteins. Invest Ophthalmol Vis Sci 41:3492-502

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