Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
1R01EY011288-01
Application #
2020022
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1996-09-30
Project End
1999-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Pathology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Flückiger, Rudolf; Cocuzzi, Enzo; Nagaraj, Ram H et al. (2018) DAF in diabetic patients is subject to glycation/inactivation at its active site residues. Mol Immunol 93:246-252
Strainic, Michael G; Shevach, Ethan M; An, Fengqi et al. (2013) Absence of signaling into CD4? cells via C3aR and C5aR enables autoinductive TGF-?1 signaling and induction of Foxp3? regulatory T cells. Nat Immunol 14:162-71
Esposito, A; Suedekum, B; Liu, J et al. (2010) Decay accelerating factor is essential for successful corneal engraftment. Am J Transplant 10:527-34
Plevka, Pavel; Hafenstein, Susan; Harris, Katherine G et al. (2010) Interaction of decay-accelerating factor with echovirus 7. J Virol 84:12665-74
Lin, Marvin; Yin, Na; Murphy, Barbara et al. (2010) Immune cell-derived c3 is required for autoimmune diabetes induced by multiple low doses of streptozotocin. Diabetes 59:2247-52
Liu, Jinbo; Lin, Feng; Strainic, Michael G et al. (2008) IFN-gamma and IL-17 production in experimental autoimmune encephalomyelitis depends on local APC-T cell complement production. J Immunol 180:5882-9
Lalli, Peter N; Strainic, Michael G; Yang, Min et al. (2008) Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis. Blood 112:1759-66
Strainic, Michael G; Liu, Jinbo; Huang, Danping et al. (2008) Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. Immunity 28:425-35
Fukuoka, Y; Strainic, M; Medof, M E (2003) Differential cytokine expression of human retinal pigment epithelial cells in response to stimulation by C5a. Clin Exp Immunol 131:248-53
Lin, Feng; Kaminski, Henry J; Conti-Fine, Bianca M et al. (2002) Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay-accelerating factor protection. J Clin Invest 110:1269-74

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