Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
1R01EY011527-01
Application #
2165836
Study Section
Special Emphasis Panel (ZRG1-VISC (01))
Project Start
1996-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Santa Barbara
Department
Type
Organized Research Units
DUNS #
City
Santa Barbara
State
CA
Country
United States
Zip Code
93106

  Publications

Isas, J Mario; Luibl, Volker; Johnson, Lincoln V et al. (2010) Soluble and mature amyloid fibrils in drusen deposits. Invest Ophthalmol Vis Sci 51:1304-10
Kochounian, Harold; Johnson, Lincoln V; Fong, Henry K W (2009) Accumulation of extracellular RGR-d in Bruch's membrane and close association with drusen at intercapillary regions. Exp Eye Res 88:1129-36
Radeke, Monte J; Peterson, Katie E; Johnson, Lincoln V et al. (2007) Disease susceptibility of the human macula: differential gene transcription in the retinal pigmented epithelium/choroid. Exp Eye Res 85:366-80
Hageman, Gregory S; Hancox, Lisa S; Taiber, Andrew J et al. (2006) Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications. Ann Med 38:592-604
Johnson, P T; Betts, K E; Radeke, M J et al. (2006) Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc Natl Acad Sci U S A 103:17456-61
Gehrs, Karen M; Anderson, Don H; Johnson, Lincoln V et al. (2006) Age-related macular degeneration--emerging pathogenetic and therapeutic concepts. Ann Med 38:450-71
Hageman, Gregory S; Anderson, Don H; Johnson, Lincoln V et al. (2005) A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A 102:7227-32
Johnson, Patrick T; Brown, Meghan N; Pulliam, Bryce C et al. (2005) Synaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusen. Invest Ophthalmol Vis Sci 46:4788-95
Malek, G; Johnson, L V; Mace, B E et al. (2005) Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proc Natl Acad Sci U S A 102:11900-5
Anderson, Don H; Talaga, Kevin C; Rivest, Alexander J et al. (2004) Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration. Exp Eye Res 78:243-56

Showing the most recent 10 out of 17 publications