Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
3R01EY013463-01A2S1
Application #
6780328
Study Section
Visual Sciences A Study Section (VISA)
Program Officer
Fisher, Richard S
Project Start
2003-02-01
Project End
2008-01-31
Budget Start
2003-02-01
Budget End
2004-01-31
Support Year
1
Fiscal Year
2003
Total Cost
$28,597
Indirect Cost
Name
University of Pittsburgh
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Block, Ethan R; Tolino, Michael A; Klarlund, Jes K (2010) Pyk2 activation triggers epidermal growth factor receptor signaling and cell motility after wounding sheets of epithelial cells. J Biol Chem 285:13372-9
Block, Ethan R; Tolino, Michael A; Lozano, Jennifer S et al. (2010) Free edges in epithelial cell sheets stimulate epidermal growth factor receptor signaling. Mol Biol Cell 21:2172-81
Block, Ethan R; Klarlund, Jes K (2008) Wounding sheets of epithelial cells activates the epidermal growth factor receptor through distinct short- and long-range mechanisms. Mol Biol Cell 19:4909-17
Lozano, Jennifer S; Chay, Edward Y; Healey, Jeffrey et al. (2008) Activation of the epidermal growth factor receptor by hydrogels in artificial tears. Exp Eye Res 86:500-5
Spix, Julie K; Chay, Edward Y; Block, Ethan R et al. (2007) Hepatocyte growth factor induces epithelial cell motility through transactivation of the epidermal growth factor receptor. Exp Cell Res 313:3319-25
Mazie, Abigail R; Spix, Julie K; Block, Ethan R et al. (2006) Epithelial cell motility is triggered by activation of the EGF receptor through phosphatidic acid signaling. J Cell Sci 119:1645-54
Block, Ethan R; Matela, Abigail R; SundarRaj, Nirmala et al. (2004) Wounding induces motility in sheets of corneal epithelial cells through loss of spatial constraints: role of heparin-binding epidermal growth factor-like growth factor signaling. J Biol Chem 279:24307-12