The objectives will include: (1) further characterization of glycolate excretion by R. rubrum, (2) preparation of mutants of R. rubrum with altered RuBP carboxylase/oxygenase, (3) characterization of the effect of histidine modification upon RuBP oxygenase, (4) elucidation of the role of small subunits in activation and catalysis by RuBP carboxylase/oxygenase and (5) separation of diastereomeric salts and lactones present in 2-carboxyhexitol-6-phosphate and -1,6-bisphosphate followed by studies of the effect of each compound upon growth of P. oxalaticus on formate.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM019972-16
Application #
3269825
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1976-06-01
Project End
1986-07-31
Budget Start
1985-08-01
Budget End
1986-07-31
Support Year
16
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Washington State University
Department
Type
Schools of Arts and Sciences
DUNS #
041485301
City
Pullman
State
WA
Country
United States
Zip Code
99164