Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM021960-19
Application #
2173841
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1978-02-01
Project End
1996-11-30
Budget Start
1993-12-01
Budget End
1996-11-30
Support Year
19
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Utah
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Huang, W M; Libbey, J L; van der Hoeven, P et al. (1998) Bipolar localization of Bacillus subtilis topoisomerase IV, an enzyme required for chromosome segregation. Proc Natl Acad Sci U S A 95:4652-7
Huang, W M (1996) Bacterial diversity based on type II DNA topoisomerase genes. Annu Rev Genet 30:79-107
Bailey, C C; Younkins, R; Huang, W M et al. (1996) Characterization of genes encoding topoisomerase IV of Mycoplasma genitalium. Gene 168:77-80
Casjens, S; Delange, M; Ley 3rd, H L et al. (1995) Linear chromosomes of Lyme disease agent spirochetes: genetic diversity and conservation of gene order. J Bacteriol 177:2769-80
Dew-Jager, K; Yu, W Q; Huang, W M (1995) The recA gene of Borrelia burgdorferi. Gene 167:137-40
Takiff, H E; Salazar, L; Guerrero, C et al. (1994) Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations. Antimicrob Agents Chemother 38:773-80
Belland, R J; Morrison, S G; Ison, C et al. (1994) Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates. Mol Microbiol 14:371-80
Samuels, D S; Marconi, R T; Huang, W M et al. (1994) gyrB mutations in coumermycin A1-resistant Borrelia burgdorferi. J Bacteriol 176:3072-5
Casjens, S; Huang, W M (1993) Linear chromosomal physical and genetic map of Borrelia burgdorferi, the Lyme disease agent. Mol Microbiol 8:967-80
Huang, W M; Ao, S Z; Casjens, S et al. (1988) A persistent untranslated sequence within bacteriophage T4 DNA topoisomerase gene 60. Science 239:1005-12

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