Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM025716-06S1
Application #
3273276
Study Section
Biophysics and Biophysical Chemistry A Study Section (BBCA)
Project Start
1978-03-01
Project End
1988-02-29
Budget Start
1987-12-01
Budget End
1988-02-29
Support Year
6
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Utah
Department
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Chiou, J S; Ueda, I (1994) Ethanol unfolds firefly luciferase while competitive inhibitors antagonize unfolding: DSC and FTIR analyses. J Pharm Biomed Anal 12:969-75
Ueda, I; Shinoda, F; Kamaya, H (1994) Temperature-dependent effects of high pressure on the bioluminescence of firefly luciferase. Biophys J 66:2107-10
Ueda, I; Chiou, J S (1994) Arrhythmogenic effect of inhalation anesthetics: biochemical heterogeneity between conduction and contractile systems and protein unfolding. Adv Pharmacol 31:223-33
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Kaminoh, Y; Nishimura, S; Kamaya, H et al. (1992) Alcohol interaction with high entropy states of macromolecules: critical temperature hypothesis for anesthesia cutoff. Biochim Biophys Acta 1106:335-43
Chiou, J S; Tatara, T; Sawamura, S et al. (1992) The alpha-helix to beta-sheet transition in poly(L-lysine): effects of anesthetics and high pressure. Biochim Biophys Acta 1119:211-7
Tamura, K; Kaminoh, Y; Kamaya, H et al. (1991) High pressure antagonism of alcohol effects on the main phase-transition temperature of phospholipid membranes: biphasic response. Biochim Biophys Acta 1066:219-24
Shibata, A; Morita, K; Yamashita, T et al. (1991) Anesthetic-protein interaction: effects of volatile anesthetics on the secondary structure of poly(L-lysine). J Pharm Sci 80:1037-41

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