Abstract

The overall goal of this project is to understand the light scattering properties of single biological cells. The precision with which changes in cell morphology can be measured with light scattering in flow cytometers will be evaluated and optimized so that light scattering can become a more useful tool for cell analysis in the clinical laboratory.
The specific aims for the current year include 1) use of the multiangle light scatter flow cytometer to study mitogen stimulation of mononuclear cell cultures, and 2) theoretical modelling studies of current and proposed detector configurations to determine their sensitivity to small changes in cell and nuclear diameters and refractive indices.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM026857-06
Application #
3274294
Study Section
(SSS)
Project Start
1979-09-30
Project End
1986-11-30
Budget Start
1985-12-01
Budget End
1986-11-30
Support Year
6
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Los Alamos National Lab
Department
Type
Organized Research Units
DUNS #
City
Los Alamos
State
NM
Country
United States
Zip Code
87545