Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM031685-15
Application #
2176260
Study Section
Special Emphasis Panel (ZRG5-BM-1 (03))
Project Start
1982-07-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Genetics
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Fagerburg, Matt V; Schauer, Grant D; Thickman, Karen R et al. (2012) PcrA-mediated disruption of RecA nucleoprotein filaments--essential role of the ATPase activity of RecA. Nucleic Acids Res 40:8416-24
Leuba, Sanford H; Anand, Syam P; Harp, Joel M et al. (2008) Expedient placement of two fluorescent dyes for investigating dynamic DNA protein interactions in real time. Chromosome Res 16:451-67
Anand, Syam P; Zheng, Haocheng; Bianco, Piero R et al. (2007) DNA helicase activity of PcrA is not required for the displacement of RecA protein from DNA or inhibition of RecA-mediated strand exchange. J Bacteriol 189:4502-9
Ruiz-Maso, J A; Anand, S P; Espinosa, M et al. (2006) Genetic and biochemical characterization of the Streptococcus pneumoniae PcrA helicase and its role in plasmid rolling circle replication. J Bacteriol 188:7416-25
Khan, Saleem A (2005) Plasmid rolling-circle replication: highlights of two decades of research. Plasmid 53:126-36
Anand, Syam P; Chattopadhyay, Anasuya; Khan, Saleem A (2005) The PcrA3 mutant binds DNA and interacts with the RepC initiator protein of plasmid pT181 but is defective in its DNA helicase and unwinding activities. Plasmid 54:104-13
Tinsley, Eowyn; Naqvi, Asma; Bourgogne, Agathe et al. (2004) Isolation of a minireplicon of the virulence plasmid pXO2 of Bacillus anthracis and characterization of the plasmid-encoded RepS replication protein. J Bacteriol 186:2717-23
Anand, Syam P; Mitra, Poulami; Naqvi, Asma et al. (2004) Bacillus anthracis and Bacillus cereus PcrA helicases can support DNA unwinding and in vitro rolling-circle replication of plasmid pT181 of Staphylococcus aureus. J Bacteriol 186:2195-9
Khan, Saleem A (2003) DNA-protein interactions during the initiation and termination of plasmid pT181 rolling-circle replication. Prog Nucleic Acid Res Mol Biol 75:113-37
Naqvi, Asma; Tinsley, Eowyn; Khan, Saleem A (2003) Purification and characterization of the PcrA helicase of Bacillus anthracis. J Bacteriol 185:6633-9

Showing the most recent 10 out of 37 publications