Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM033342-03
Application #
3282935
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1984-04-01
Project End
1987-03-31
Budget Start
1986-04-01
Budget End
1987-03-31
Support Year
3
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
Schools of Medicine
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Suh, K; Gabel, C A; Bergmann, J E (1992) Identification of a novel mechanism for the removal of glucose residues from high mannose-type oligosaccharides. J Biol Chem 267:21671-7
Einstein, R; Gabel, C A (1991) Cell- and ligand-specific dephosphorylation of acid hydrolases: evidence that the mannose 6-phosphatase is controlled by compartmentalization. J Cell Biol 112:81-94
Hendricks, L C; Gabel, C A; Suh, K et al. (1991) A 58-kDa resident protein of the cis Golgi cisterna is not terminally glycosylated. J Biol Chem 266:17559-65
Lazzarino, D; Gabel, C A (1990) beta-Glucuronidase is transported slowly to lysosomes in BW5147 mouse lymphoma cells: evidence that the prelysosomal enzyme is not restricted to the endoplasmic reticulum. Arch Biochem Biophys 282:100-9
Lazzarino, D; Gabel, C A (1990) Protein determinants impair recognition of procathepsin L phosphorylated oligosaccharides by the cation-independent mannose 6-phosphate receptor. J Biol Chem 265:11864-71
Borden, L A; Einstein, R; Gabel, C A et al. (1990) Acidification-dependent dissociation of endocytosed insulin precedes that of endocytosed proteins bearing the mannose 6-phosphate recognition marker. J Biol Chem 265:8497-504
Gabel, C A; Den, H; Ambron, R T (1989) Characterization of protein-linked glycoconjugates produced by identified neurons of Aplysia californica. J Neurobiol 20:530-48
Lazzarino, D A; Gabel, C A (1989) Mannose processing is an important determinant in the assembly of phosphorylated high mannose-type oligosaccharides. J Biol Chem 264:5015-23
O'Brien, D A; Gabel, C A; Rockett, D L et al. (1989) Receptor-mediated endocytosis and differential synthesis of mannose 6-phosphate receptors in isolated spermatogenic and sertoli cells. Endocrinology 125:2973-84
Einstein, R; Gabel, C A (1989) Serum factors alter the extent of dephosphorylation of ligands endocytosed via the mannose 6-phosphate/insulin-like growth factor II receptor. J Cell Biol 109:1037-46

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