Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM033776-09S1
Application #
3283754
Study Section
Biochemistry Study Section (BIO)
Project Start
1984-07-01
Project End
1994-06-30
Budget Start
1992-07-01
Budget End
1993-06-30
Support Year
9
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Krone, U E; McFarlan, S C; Hogenkamp, H P (1994) Purification and partial characterization of a putative thymidylate synthase from Methanobacterium thermoautotrophicum. Eur J Biochem 220:789-94
Loida, P J; Sligar, S G (1993) Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions. Biochemistry 32:11530-8
Ong, S P; McFarlan, S C; Hogenkamp, H P (1993) 2'-C-methyladenosine and 2'-C-methyluridine 5'-diphosphates are mechanism-based inhibitors of ribonucleoside diphosphate reductase from Corynebacterium nephridii. Biochemistry 32:11397-404
Ong, S P; Nelson, L S; Hogenkamp, H P (1992) Synthesis of 3'-C-methyladenosine and 3'-C-methyluridine diphosphates and their interaction with the ribonucleoside diphosphate reductase from Corynebacterium nephridii. Biochemistry 31:11210-5
Schallreuter, K U; Elgren, T E; Nelson Jr, L S et al. (1992) Ribonucleotide diphosphate reductase from human metastatic melanoma. Melanoma Res 2:393-400
McFarlan, S C; Terrell, C A; Hogenkamp, H P (1992) The purification, characterization, and primary structure of a small redox protein from Methanobacterium thermoautotrophicum, an archaebacterium. J Biol Chem 267:10561-9
Sze, I S; McFarlan, S C; Spormann, A et al. (1992) A possible new class of ribonucleotide reductase from Methanobacterium thermoautotrophicum. Biochem Biophys Res Commun 184:1101-7
McFarlan, S C; Hogenkamp, H P; Eccleston, E D et al. (1989) Purification, characterization and revised amino acid sequence of a second thioredoxin from Corynebacterium nephridii. Eur J Biochem 179:389-98
Mirkin, B L; O'Dea, R F; Hogenkamp, H P (1987) Cytotoxic action of adenosine nucleoside and dialdehyde analogues on murine neuroblastoma in tissue culture: structure-activity relationships. Cancer Res 47:3650-5
Lim, C J; Fuchs, J A; McFarlan, S C et al. (1987) Cloning, expression, and nucleotide sequence of a gene encoding a second thioredoxin from Corynebacterium nephridii. J Biol Chem 262:12114-9

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