Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
7R01GM034090-10
Application #
3284563
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1984-07-01
Project End
1994-06-30
Budget Start
1993-01-01
Budget End
1994-06-30
Support Year
10
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Wayne State University
Department
Type
Other Domestic Higher Education
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Tanaka, S; Kaytes, P; Kurkinen, M (1993) An enhancer for transcription of collagen IV genes is activated by F9 cell differentiation. J Biol Chem 268:8862-70
Otani, Y; Quinones, S; Saus, J et al. (1990) Cycloheximide induces stromelysin mRNA in cultured human fibroblasts. Eur J Biochem 192:75-9
Buttice, G; Kaytes, P; D'Armiento, J et al. (1990) Evolution of collagen IV genes from a 54-base pair exon: a role for introns in gene evolution. J Mol Evol 30:479-88
Saus, J; Quinones, S; MacKrell, A et al. (1989) The complete primary structure of mouse alpha 2(IV) collagen. Alignment with mouse alpha 1(IV) collagen. J Biol Chem 264:6318-24
Quinones, S; Saus, J; Otani, Y et al. (1989) Transcriptional regulation of human stromelysin. J Biol Chem 264:8339-44
Muthukumaran, G; Blumberg, B; Kurkinen, M (1989) The complete primary structure for the alpha 1-chain of mouse collagen IV. Differential evolution of collagen IV domains. J Biol Chem 264:6310-7
Saus, J; Quinones, S; Otani, Y et al. (1988) The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin. J Biol Chem 263:6742-5
Hostikka, S L; Kurkinen, M; Tryggvason, K (1987) Nucleotide sequence coding for the human type IV collagen alpha 2 chain cDNA reveals extensive homology with the NC-1 domain of alpha 1 (IV) but not with the collagenous domain or 3'-untranslated region. FEBS Lett 216:281-6
Boot-Handford, R P; Kurkinen, M; Prockop, D J (1987) Steady-state levels of mRNAs coding for the type IV collagen and laminin polypeptide chains of basement membranes exhibit marked tissue-specific stoichiometric variations in the rat. J Biol Chem 262:12475-8
Kurkinen, M; Condon, M R; Blumberg, B et al. (1987) Extensive homology between the carboxyl-terminal peptides of mouse alpha 1(IV) and alpha 2(IV) collagen. J Biol Chem 262:8496-9

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