We plan to isolate, purify and determine the structures of compounds which have a direct or indirect bearing with cancer, cell growth regulation and other biological activities. If feasible the structural studies will be followed by bioorganic studies. The compounds involved include adduct resulting from binding of carcinogens to nucleic acids, various nucleic acid base derivatives, marine neurotoxins, cell growth regulators, and an antisickling agent.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM034509-19
Application #
3285654
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1985-01-01
Project End
1988-12-31
Budget Start
1988-01-01
Budget End
1988-12-31
Support Year
19
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
Graduate Schools
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
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