Our objective is to determine the three-dimensional structure of bacterial luciferase by the method of X-ray crystallography. Recent success in obtaining large crystals of the protein makes this a feasible undertaking. This will be the first known structure of any bioluminescent system and will be a major step toward understanding the phenomenon of light emission. The study will also contribute to our understanding of the structure and function of biological systems in general and flavin-proteins in particular.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM035114-01
Application #
3287235
Study Section
Biophysics and Biophysical Chemistry B Study Section (BBCB)
Project Start
1985-08-01
Project End
1990-07-31
Budget Start
1985-08-01
Budget End
1986-07-31
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Oregon
Department
Type
Graduate Schools
DUNS #
948117312
City
Eugene
State
OR
Country
United States
Zip Code
97403