Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM035719-01
Application #
3288812
Study Section
Biophysics and Biophysical Chemistry B Study Section (BBCB)
Project Start
1986-01-01
Project End
1990-12-31
Budget Start
1986-01-01
Budget End
1986-12-31
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Type
Schools of Medicine
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Komarov, A M; Lai, C S (1995) Detection of nitric oxide production in mice by spin-trapping electron paramagnetic resonance spectroscopy. Biochim Biophys Acta 1272:29-36
Lai, C S; Komarov, A M (1994) Spin trapping of nitric oxide produced in vivo in septic-shock mice. FEBS Lett 345:120-4
Komarov, A M; Joseph, J; Lai, C S (1994) In vivo pharmacokinetics of nitroxides in mice. Biochem Biophys Res Commun 201:1035-42
Lai, C S; Wolff, C E; Novello, D et al. (1993) Solution structure of human plasma fibronectin under different solvent conditions. Fluorescence energy transfer, circular dichroism and light-scattering studies. J Mol Biol 230:625-40
Kar, L; Lai, C S; Wolff, C E et al. (1993) 1H NMR-based determination of the three-dimensional structure of the human plasma fibronectin fragment containing inter-chain disulfide bonds. J Biol Chem 268:8580-9
Komarov, A; Mattson, D; Jones, M M et al. (1993) In vivo spin trapping of nitric oxide in mice. Biochem Biophys Res Commun 195:1191-8
Narasimhan, C; Lai, C S (1991) Differential behavior of the two free sulfhydryl groups of human plasma fibronectin: effects of environmental factors. Biopolymers 31:1159-70
Joseph, J; Shih, C C; Lai, C S (1991) Synthesis of the spin-labeled derivative of an ether-linked phospholipid possessing high antineoplastic activity. Chem Phys Lipids 58:19-26
Squier, T C; Mahaney, J E; Yin, J J et al. (1991) Resolution of phospholipid conformational heterogeneity in model membranes by spin-label EPR and frequency-domain fluorescence spectroscopy. Biophys J 59:654-69
Wolff, C E; Lai, C S (1990) Inter-sulfhydryl distances in plasma fibronectin determined by fluorescence energy transfer: effect of environmental factors. Biochemistry 29:3354-61

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