Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM035989-07
Application #
2178186
Study Section
Biochemistry Study Section (BIO)
Project Start
1987-08-01
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Texas Austin
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
Austin
State
TX
Country
United States
Zip Code
78712
Robertus, J D; Monzingo, A F; Marcotte, E M et al. (1998) Structural analysis shows five glycohydrolase families diverged from a common ancestor. J Exp Zool 282:127-32
Hollis, T; Honda, Y; Fukamizo, T et al. (1997) Kinetic analysis of barley chitinase. Arch Biochem Biophys 344:335-42
Chaddock, J A; Monzingo, A F; Robertus, J D et al. (1996) Major structural differences between pokeweed antiviral protein and ricin A-chain do not account for their differing ribosome specificity. Eur J Biochem 235:159-66
Day, P J; Ernst, S R; Frankel, A E et al. (1996) Structure and activity of an active site substitution of ricin A chain. Biochemistry 35:11098-103
Pishko, E J; Potter, K A; Robertus, J D (1995) Site-directed mutagenesis of intersubunit boundary residues in histidine decarboxylase, a pH-dependent allosteric enzyme. Biochemistry 34:6069-73
Hart, P J; Pfluger, H D; Monzingo, A F et al. (1995) The refined crystal structure of an endochitinase from Hordeum vulgare L. seeds at 1.8 A resolution. J Mol Biol 248:402-13
Pishko, E J; Robertus, J D (1993) Site-directed alteration of three active-site residues of a pyruvoyl-dependent histidine decarboxylase. Biochemistry 32:4943-8
Robertus, J D (1992) The structure of plant toxins as a guide to rational design. Targeted Diagn Ther 7:133-49
Robertus, J (1991) The structure and action of ricin, a cytotoxic N-glycosidase. Semin Cell Biol 2:23-30
Katzin, B J; Collins, E J; Robertus, J D (1991) Structure of ricin A-chain at 2.5 A. Proteins 10:251-9

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