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Iyer, K R; Jones, J P; Darbyshire, J F et al. (1997) Intramolecular isotope effects for benzylic hydroxylation of isomeric xylenes and 4,4'-dimethylbiphenyl by cytochrome P450: relationship between distance of methyl groups and masking of the intrinsic isotope effect. Biochemistry 36:7136-43
|
|
Darbyshire, J F; Iyer, K R; Grogan, J et al. (1996) Substrate probe for the mechanism of aromatic hydroxylation catalyzed by cytochrome P450. Drug Metab Dispos 24:1038-45
|
|
Carlson, T J; Jones, J P; Peterson, L et al. (1995) Stereoselectivity and isotope effects associated with cytochrome P450-catalyzed oxidation of (S)-nicotine. The possibility of initial hydrogen atom abstraction in the formation of the delta 1', 5-nicotinium ion. Drug Metab Dispos 23:749-56
|
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Kunze, K L; Trager, W F (1993) Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline. Chem Res Toxicol 6:649-56
|
|
Korzekwa, K R; Trager, W F; Mancewicz, J et al. (1993) Studies on the mechanism of aromatase and other cytochrome P450 mediated deformylation reactions. J Steroid Biochem Mol Biol 44:367-73
|
|
Korzekwa, K R; Trager, W F; Smith, S J et al. (1991) Theoretical studies on the mechanism of conversion of androgens to estrogens by aromatase. Biochemistry 30:6155-62
|
|
Ottoboni, S; Carlson, T J; Trager, W F et al. (1990) Studies on the cytochrome P-450 catalyzed ring alpha-carbon oxidation of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Chem Res Toxicol 3:423-7
|
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Korzekwa, K; Howald, W N; Trager, W F (1990) The use of Brauman's least squares approach for the quantification of deuterated chlorophenols. Biomed Environ Mass Spectrom 19:211-7
|
|
Korzekwa, K R; Trager, W F; Nagata, K et al. (1990) Isotope effect studies on the mechanism of the cytochrome P-450IIA1-catalyzed formation of delta 6-testosterone from testosterone. Drug Metab Dispos 18:974-9
|
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Jones, J P; Rettie, A E; Trager, W F (1990) Intrinsic isotope effects suggest that the reaction coordinate symmetry for the cytochrome P-450 catalyzed hydroxylation of octane is isozyme independent. J Med Chem 33:1242-6
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