Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM037279-02S1
Application #
3292554
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1986-07-01
Project End
1991-06-30
Budget Start
1988-05-10
Budget End
1988-06-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Reilly, R F; Hildebrandt, F; Biemesderfer, D et al. (1991) cDNA cloning and immunolocalization of a Na(+)-H+ exchanger in LLC-PK1 renal epithelial cells. Am J Physiol 261:F1088-94
Igarashi, P; Reilly, R F; Hildebrandt, F et al. (1991) Molecular biology of renal Na(+)-H+ exchangers. Kidney Int Suppl 33:S84-9
Reilly, R F; Haggerty, J G; Aronson, P S et al. (1991) Increased Na(+)-H+ antiporter activity in apical membrane vesicles from mutant LLC-PK1 cells. Am J Physiol 260:C738-44
Huot, S J; Cassel, D; Igarashi, P et al. (1989) Identification and purification of a renal amiloride-binding protein with properties of the Na+-H+ exchanger. J Biol Chem 264:683-6
Haggerty, J G; Agarwal, N; Reilly, R F et al. (1988) Pharmacologically different Na/H antiporters on the apical and basolateral surfaces of cultured porcine kidney cells (LLC-PK1). Proc Natl Acad Sci U S A 85:6797-801
Haggerty, J G; Agarwal, N; Cragoe Jr, E J et al. (1988) LLC-PK1 mutant with increased Na+-H+ exchange and decreased sensitivity to amiloride. Am J Physiol 255:C495-501