Abstract

The physical identification and characterization of certain maize transposable elements has made a range of biological phenomena accessible to molecular study. We propose two lines of research pertaining to the Ac/Ds controlling element system. First, we have evidence that activation of Ac elements in the cell may be controlled by structural and/or methylation changes. We propose to study the structure of cryptic copies of Ac and Ds elements in the maize genome and to induce activation of Ac to examine the mechanism of activation. Second, we propose to use insertions of Ac and Ds to clone and characterize the R locus of maize.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
7R01GM038148-01
Application #
3294244
Study Section
Genetics Study Section (GEN)
Project Start
1986-07-01
Project End
1988-06-30
Budget Start
1986-07-01
Budget End
1987-06-30
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Yale University
Department
Type
Schools of Arts and Sciences
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Persson, Bengt; Kallberg, Yvonne; Bray, James E et al. (2009) The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Chem Biol Interact 178:94-8
Acosta, Iván F; Laparra, Hélène; Romero, Sandra P et al. (2009) tasselseed1 is a lipoxygenase affecting jasmonic acid signaling in sex determination of maize. Science 323:262-5
Schierwater, Bernd; Eitel, Michael; Jakob, Wolfgang et al. (2009) Concatenated analysis sheds light on early metazoan evolution and fuels a modern ""urmetazoon"" hypothesis. PLoS Biol 7:e20
Kim, Jong Cheol; Laparra, Helene; Calderon-Urrea, Alejandro et al. (2007) Cell cycle arrest of stamen initials in maize sex determination. Genetics 177:2547-51
Wu, Xiaoqiu; Knapp, Stefan; Stamp, Anna et al. (2007) Biochemical characterization of TASSELSEED 2, an essential plant short-chain dehydrogenase/reductase with broad spectrum activities. FEBS J 274:1172-82
Cadavid, Luis F; Powell, Anahid E; Nicotra, Matthew L et al. (2004) An invertebrate histocompatibility complex. Genetics 167:357-65
Curie, C; Panaviene, Z; Loulergue, C et al. (2001) Maize yellow stripe1 encodes a membrane protein directly involved in Fe(III) uptake. Nature 409:346-9
Schultes, N P; Brutnell, T P; Allen, A et al. (1996) Leaf permease1 gene of maize is required for chloroplast development. Plant Cell 8:463-75
Brutnell, T P; Dellaporta, S L (1994) Somatic inactivation and reactivation of Ac associated with changes in cytosine methylation and transposase expression. Genetics 138:213-25
Dellaporta, S L; Calderon-Urrea, A (1994) The sex determination process in maize. Science 266:1501-5

Showing the most recent 10 out of 16 publications