Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040639-07
Application #
2180496
Study Section
Molecular Biology Study Section (MBY)
Project Start
1988-08-01
Project End
1998-06-30
Budget Start
1995-12-01
Budget End
1998-06-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
City of Hope/Beckman Research Institute
Department
Type
DUNS #
City
Duarte
State
CA
Country
United States
Zip Code
91010
Chandra, Manasa; Zang, Shengbing; Li, Haiqing et al. (2012) Nuclear translocation of type I transforming growth factor ýý receptor confers a novel function in RNA processing. Mol Cell Biol 32:2183-95
Gencheva, Marieta; Lin, Ting-Yu; Wu, Xiwei et al. (2010) Nuclear retention of unspliced pre-mRNAs by mutant DHX16/hPRP2, a spliceosomal DEAH-box protein. J Biol Chem 285:35624-32
Gencheva, Marieta; Kato, Mitsuo; Newo, Alain N S et al. (2010) Contribution of DEAH-box protein DHX16 in human pre-mRNA splicing. Biochem J 429:25-32
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Huang, Ching-Jung; Tang, Zhaohua; Lin, Ren-Jang et al. (2007) Phosphorylation by SR kinases regulates the binding of PTB-associated splicing factor (PSF) to the pre-mRNA polypyrimidine tract. FEBS Lett 581:223-32
Li, Chunxia; Kato, Mitsuo; Shiue, Lily et al. (2006) Cell type and culture condition-dependent alternative splicing in human breast cancer cells revealed by splicing-sensitive microarrays. Cancer Res 66:1990-9
Silverman, Edward J; Maeda, Ayaka; Wei, Janet et al. (2004) Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Mol Cell Biol 24:10101-10
Edwalds-Gilbert, Gretchen; Kim, Dong-Ho; Silverman, Edward et al. (2004) Definition of a spliceosome interaction domain in yeast Prp2 ATPase. RNA 10:210-20
Silverman, Edward; Edwalds-Gilbert, Gretchen; Lin, Ren-Jang (2003) DExD/H-box proteins and their partners: helping RNA helicases unwind. Gene 312:1-16
Edwalds-Gilbert, G; Kim, D H; Kim, S H et al. (2000) Dominant negative mutants of the yeast splicing factor Prp2 map to a putative cleft region in the helicase domain of DExD/H-box proteins. RNA 6:1106-19

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