Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040714-09
Application #
2180549
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1988-07-01
Project End
1997-07-31
Budget Start
1996-07-01
Budget End
1997-07-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Hildebrandt, Emily R; Gheber, Larisa; Kingsbury, Tami et al. (2006) Homotetrameric form of Cin8p, a Saccharomyces cerevisiae kinesin-5 motor, is essential for its in vivo function. J Biol Chem 281:26004-13
Hildebrandt, E R; Hoyt, M A (2001) Cell cycle-dependent degradation of the Saccharomyces cerevisiae spindle motor Cin8p requires APC(Cdh1) and a bipartite destruction sequence. Mol Biol Cell 12:3402-16
Hildebrandt, E R; Hoyt, M A (2000) Mitotic motors in Saccharomyces cerevisiae. Biochim Biophys Acta 1496:99-116
Gheber, L; Kuo, S C; Hoyt, M A (1999) Motile properties of the kinesin-related Cin8p spindle motor extracted from Saccharomyces cerevisiae cells. J Biol Chem 274:9564-72
Cottingham, F R; Gheber, L; Miller, D L et al. (1999) Novel roles for saccharomyces cerevisiae mitotic spindle motors. J Cell Biol 147:335-50
Saunders, W; Lengyel, V; Hoyt, M A (1997) Mitotic spindle function in Saccharomyces cerevisiae requires a balance between different types of kinesin-related motors. Mol Biol Cell 8:1025-33
Geiser, J R; Schott, E J; Kingsbury, T J et al. (1997) Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol Biol Cell 8:1035-50
Cottingham, F R; Hoyt, M A (1997) Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J Cell Biol 138:1041-53
Hoyt, M A; Macke, J P; Roberts, B T et al. (1997) Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability. Genetics 146:849-57
Hoyt, M A; He, L; Totis, L et al. (1993) Loss of function of Saccharomyces cerevisiae kinesin-related CIN8 and KIP1 is suppressed by KAR3 motor domain mutations. Genetics 135:35-44

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