Catalytic Antibodies for Peptide Synthesis

Agency: National Institute of Health (NIH)
Institute: National Institute of General Medical Sciences (NIGMS)
Type: Research Project (R01)
Project #: 2R01GM045611-04A1
Application #: 2183286
Study Section: Bio-Organic and Natural Products Chemistry Study Section (BNP)


NIH 1998 R01 GM	Catalytic Antibodies for Peptide Synthesis Hirschmann, Ralph F. / University of Pennsylvania
NIH 1997 R01 GM	Catalytic Antibodies for Peptide Synthesis Hirschmann, Ralph F. / University of Pennsylvania
NIH 1996 R01 GM	Catalytic Antibodies for Peptide Synthesis Hirschmann, Ralph F. / University of Pennsylvania
NIH 1993 R01 GM	Catalytic Antibodies for Peptide Synthesis Hirschmann, Ralph F. / University of Pennsylvania
NIH 1992 R01 GM	Catalytic Antibodies for Peptide Synthesis Hirschmann, Ralph F. / University of Pennsylvania
NIH 1991 R01 GM	Catalytic Antibodies for Peptide Synthesis Hirschmann, Ralph F. / University of Pennsylvania

Savinov, Sergey N; Hirschmann, Ralph; Benkovic, Stephen J et al. (2003) Investigation of an antibody-ligase. Evidence for strain-induced catalysis. Bioorg Med Chem Lett 13:1321-4

Smithrud, D B; Benkovic, P A; Benkovic, S J et al. (2000) Cyclic peptide formation catalyzed by an antibody ligase. Proc Natl Acad Sci U S A 97:1953-8

Hirschmann, R; Smith 3rd, A B; Taylor, C M et al. (1994) Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids. Science 265:234-7