Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM046535-06
Application #
2899612
Study Section
Project Start
1998-07-01
Project End
1999-04-30
Budget Start
1998-04-01
Budget End
1999-03-31
Support Year
6
Fiscal Year
1998
Total Cost
Indirect Cost
Livesay, Dennis R; Subramaniam, Shankar (2004) Conserved sequence and structure association motifs in antibody-protein and antibody-hapten complexes. Protein Eng Des Sel 17:463-72
Livesay, Dennis R; Jambeck, Per; Rojnuckarin, Atipat et al. (2003) Conservation of electrostatic properties within enzyme families and superfamilies. Biochemistry 42:3464-73
Khare, Sangeeta; Banai, Yona; Gokulan, Kuppan et al. (2003) Early changes in metabolism of leukemic cell lines upon induction of apoptosis by cytotoxic drugs. Eur J Pharmacol 465:23-30
Linthicum, D S; Patel, J; Cairns, N (2001) Antibody-based fluorescence polarization assay to screen combinatorial libraries for sweet taste compounds. Comb Chem High Throughput Screen 4:431-8
Khare, S; Gokulan, K; Linthicum, D S (2001) Cellular responses of NG108-15 and SK-N-MC lines to sweet and bitter tastants as measured by extracellular acidification rates. J Neurosci Res 63:64-71
Linthicum, D S (2001) Ultrastructural effects of silicic acid on primary lung fibroblasts in tissue culture. Tissue Cell 33:514-23
Linthicum, D S; Tetin, S Y; Anchin, J M et al. (2001) Antibody-ligand interactions: computational modeling and correlation with biophysical measurements. Comb Chem High Throughput Screen 4:439-49
Herrgard, S; Gibas, C J; Subramaniam, S (2000) Role of an electrostatic network of residues in the enzymatic action of the Rhizomucor miehei lipase family. Biochemistry 39:2921-30
Khare, S; Gokulan, K; Linthicum, D S (2000) Vasoactive amine responses in murine cerebrovascular endothelial cells as measured by extracellular acidification rates. J Neurosci Res 60:356-61
Chen, J; Pattarawarapan, M; Zhang, A J et al. (2000) Solution- and solid-phase syntheses of substituted guanidinocarboxylic acids. J Comb Chem 2:276-81

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