Binding of HIV 1 Sequences by Cyclic Oligonucleotides - Eric Kool

Abstract

Funding Agency

Agency: National Institute of Health (NIH)
Institute: National Institute of General Medical Sciences (NIGMS)
Type: Research Project (R01)
Project #: 5R01GM046625-06
Application #: 2184126
Study Section: AIDS and Related Research Study Section 4 (ARRD)

Project Start: 1991-07-01
Project End: 1997-07-31
Budget Start: 1996-07-01
Budget End: 1997-07-31
Support Year: 6
Fiscal Year: 1996
Total Cost
Indirect Cost

Institution

Name: University of Rochester
Department: Chemistry
Type: Schools of Arts and Sciences
DUNS #: 208469486

City: Rochester
State: NY
Country: United States
Zip Code: 14627

Related projects


NIH 1999 R01 GM	Topologically Modified Oligonucleotides Targeted to HIV1 Kool, Eric T. / University of Rochester
NIH 1999 R01 GM	Topologically Modified Oligonucleotides Targeted to HIV1 Kool, Eric T. / Stanford University
NIH 1998 R01 GM	Topologically Modified Oligonucleotides Targeted to HIV1 Kool, Eric T. / University of Rochester
NIH 1997 R01 GM	Topologically Modified Oligonucleotides Targeted to HIV1 Kool, Eric T. / University of Rochester
NIH 1996 R01 GM	Binding of HIV 1 Sequences by Cyclic Oligonucleotides Kool, Eric T. / University of Rochester
NIH 1995 R01 GM	Binding of HIV 1 Sequences by Cyclic Oligonucleotides Kool, Eric T. / University of Rochester
NIH 1994 R01 GM	Binding of HIV 1 Sequences by Cyclic Oligonucleotides Kool, Eric T. / University of Rochester
NIH 1993 R01 GM	Antisense Binding of HIV-1 by Circular Oligonucleotides Kool, Eric T. / University of Rochester
NIH 1992 R01 GM	Antisense Binding of HIV-1 by Circular Oligonucleotides Kool, Eric T. / University of Rochester
NIH 1991 R01 GM	Antisense Binding of HIV-1 by Circular Oligonucleotides Kool, Eric T. / University of Rochester

Publications

Mohsen, Michael G; Kool, Eric T (2016) The Discovery of Rolling Circle Amplification and Rolling Circle Transcription. Acc Chem Res 49:2540-2550

Ohmichi, T; Kool, E T (2000) The virtues of self-binding: high sequence specificity for RNA cleavage by self-processed hammerhead ribozymes. Nucleic Acids Res 28:776-83

Xu, Y; Kool, E T (1999) High sequence fidelity in a non-enzymatic DNA autoligation reaction. Nucleic Acids Res 27:875-81

Xu, Y; Kool, E T (1998) Chemical and enzymatic properties of bridging 5'-S-phosphorothioester linkages in DNA. Nucleic Acids Res 26:3159-64

Wang, S; Xu, Y; Kool, E T (1997) Recognition of RNA by triplex formation: divergent effects of pyrimidine C-5 methylation. Bioorg Med Chem 5:1043-50

Kool, E T (1996) Circular oligonucleotides: new concepts in oligonucleotide design. Annu Rev Biophys Biomol Struct 25:1-28

Wang, S; Friedman, A E; Kool, E T (1995) Origins of high sequence selectivity: a stopped-flow kinetics study of DNA/RNA hybridization by duplex- and triplex-forming oligonucleotides. Biochemistry 34:9774-84

Wang, S; Kool, E T (1994) Circular RNA oligonucleotides. Synthesis, nucleic acid binding properties, and a comparison with circular DNAs. Nucleic Acids Res 22:2326-33

Booher, M A; Wang, S; Kool, E T (1994) Base pairing and steric interactions between pyrimidine strand bridging loops and the purine strand in DNA pyrimidine.purine.pyrimidine triplexes. Biochemistry 33:4645-51

Wang, S; Booher, M A; Kool, E T (1994) Stabilities of nucleotide loops bridging the pyrimidine strands in DNA pyrimidine.purine.pyrimidine triplexes: special stability of the CTTTG loop. Biochemistry 33:4639-44

Showing the most recent 10 out of 11 publications

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