Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM046902-04
Application #
2184393
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1992-02-01
Project End
1997-01-31
Budget Start
1995-02-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Hintermann, Edith; Yang, Neng; O'Sullivan, Deirdre et al. (2005) Integrin alpha6beta4-erbB2 complex inhibits haptotaxis by up-regulating E-cadherin cell-cell junctions in keratinocytes. J Biol Chem 280:8004-15
Koshikawa, Naohiko; Minegishi, Tomoko; Sharabi, Andrew et al. (2005) Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain. J Biol Chem 280:88-93
Bilban, Martin; Ghaffari-Tabrizi, Nassim; Hintermann, Edith et al. (2004) Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts. J Cell Sci 117:1319-28
Hendrix, Mary J C; Seftor, Elisabeth A; Kirschmann, Dawn A et al. (2003) Remodeling of the microenvironment by aggressive melanoma tumor cells. Ann N Y Acad Sci 995:151-61
Schenk, Susann; Hintermann, Edith; Bilban, Martin et al. (2003) Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution. J Cell Biol 161:197-209
Bilban, Martin; Buehler, Lukas K; Head, Steven et al. (2002) Normalizing DNA microarray data. Curr Issues Mol Biol 4:57-64
Hintermann, Edith; Haake, Susan Kinder; Christen, Urs et al. (2002) Discrete proteolysis of focal contact and adherens junction components in Porphyromonas gingivalis-infected oral keratinocytes: a strategy for cell adhesion and migration disabling. Infect Immun 70:5846-56
Seftor, R E; Seftor, E A; Koshikawa, N et al. (2001) Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma. Cancer Res 61:6322-7
Hintermann, E; Bilban, M; Sharabi, A et al. (2001) Inhibitory role of alpha 6 beta 4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on alpha 3 beta 1 integrin. J Cell Biol 153:465-78
Kiosses, W B; Hahn, K M; Giannelli, G et al. (2001) Characterization of morphological and cytoskeletal changes in MCF10A breast epithelial cells plated on laminin-5: comparison with breast cancer cell line MCF7. Cell Commun Adhes 8:29-44

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