Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM048800-03
Application #
2186308
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1994-01-01
Project End
1998-06-30
Budget Start
1996-01-01
Budget End
1998-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Wu, W; Schmidt, T R; Goodman, M et al. (2000) Molecular evolution of cytochrome c oxidase subunit I in primates: is there coevolution between mitochondrial and nuclear genomes? Mol Phylogenet Evol 17:294-304
Wong-Riley, M; Guo, A; Bachman, N J et al. (2000) Human COX6A1 gene: promoter analysis, cDNA isolation and expression in the monkey brain. Gene 247:63-75
Bachman, N J; Wu, W; Schmidt, T R et al. (1999) The 5' region of the COX4 gene contains a novel overlapping gene, NOC4. Mamm Genome 10:506-12
Schmidt, T R; Goodman, M; Grossman, L I (1999) Molecular evolution of the COX7A gene family in primates. Mol Biol Evol 16:619-26
Makris, G J; Lomax, M I (1997) The gene encoding the heart/muscle isoform of cytochrome c oxidase subunit VIII maps to mouse chromosome 7. Mamm Genome 8:453-4
Wu, W; Goodman, M; Lomax, M I et al. (1997) Molecular evolution of cytochrome c oxidase subunit IV: evidence for positive selection in simian primates. J Mol Evol 44:477-91
Grossman, L I; Lomax, M I (1997) Nuclear genes for cytochrome c oxidase. Biochim Biophys Acta 1352:174-92
Schmidt, T R; Jaradat, S A; Goodman, M et al. (1997) Molecular evolution of cytochrome c oxidase: rate variation among subunit VIa isoforms. Mol Biol Evol 14:595-601
Bachman, N J; Riggs, P K; Siddiqui, N et al. (1997) Structure of the human gene (COX6A2) for the heart/muscle isoform of cytochrome c oxidase subunit VIa and its chromosomal location in humans, mice, and cattle. Genomics 42:146-51
Makris, G J; Lomax, M I (1996) Sequence of the cDNA for the liver/non-muscle isoform of mouse cytochrome-c oxidase subunit VIII. Biochim Biophys Acta 1308:197-200

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