Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM048802-03
Application #
2186311
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1994-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Rutgers University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901

  Publications

Shallop, Anthony J; Gaffney, Barbara L; Jones, Roger A (2004) Use of both direct and indirect 13C tags for probing nitrogen interactions in hairpin ribozyme models by 15N NMR. Nucleosides Nucleotides Nucleic Acids 23:273-80
Li, Tsai-Kun; Barbieri, Christopher M; Lin, Hsin-Chin et al. (2004) Drug targeting of HIV-1 RNA.DNA hybrid structures: thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication. Biochemistry 43:9732-42
Shallop, Anthony J; Gaffney, Barbara L; Jones, Roger A (2003) Use of 13C as an indirect tag in 15N specifically labeled nucleosides. Syntheses of [8-13C-1,7,NH2-15N3]adenosine, -guanosine, and their deoxy analogues. J Org Chem 68:8657-61
Barbieri, Christopher M; Li, Tsai-Kun; Guo, Susan et al. (2003) Aminoglycoside complexation with a DNA.RNA hybrid duplex: the thermodynamics of recognition and inhibition of RNA processing enzymes. J Am Chem Soc 125:6469-77
Gu, Feng; Stillwell, W G; Wishnok, John S et al. (2002) Peroxynitrite-induced reactions of synthetic oligo 2'-deoxynucleotides and DNA containing guanine: formation and stability of a 5-guanidino-4-nitroimidazole lesion. Biochemistry 41:7508-18
Mukerji, Ishita; Williams, Alison P (2002) UV resonance Raman and circular dichroism studies of a DNA duplex containing an A(3)T(3) tract: evidence for a premelting transition and three-centered H-bonds. Biochemistry 41:69-77
Kuryavyi, V; Majumdar, A; Shallop, A et al. (2001) A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple. J Mol Biol 310:181-94
Veldhuyzen, W F; Shallop, A J; Jones, R A et al. (2001) Thermodynamic versus kinetic products of DNA alkylation as modeled by reaction of deoxyadenosine. J Am Chem Soc 123:11126-32
Kettani, A; Gorin, A; Majumdar, A et al. (2000) A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations. J Mol Biol 297:627-44
Kuryavyi, V; Kettani, A; Wang, W et al. (2000) A diamond-shaped zipper-like DNA architecture containing triads sandwiched between mismatches and tetrads. J Mol Biol 295:455-69

Showing the most recent 10 out of 14 publications