Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050764-03
Application #
2188810
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1994-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Physiology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Rembold, Christopher M; Ripley, Marcia L; Meeks, Melissa K et al. (2005) Serine 68 phospholemman phosphorylation during forskolin-induced swine carotid artery relaxation. J Vasc Res 42:483-91
Kutchai, H; Geddis, L M (2001) Inhibition of the Na,K-ATPase of canine renal medulla by several local anesthetics. Pharmacol Res 43:399-403
Kutchai, H; Geddis, L M; Farley, R A (2000) Effects of local anaesthetics on the activity of the Na,K-ATPase of canine renal medulla. Pharmacol Res 41:7-Jan
Reddy, L G; Shi, Y; Kutchai, H et al. (1999) An autoinhibitory peptide from the erythrocyte Ca-ATPase aggregates and inhibits both muscle Ca-ATPase isoforms. Biophys J 76:3058-65
Kutchai, H; Geddis, L M; Farley, R A (1999) Effects of general anaesthetics on the activity of the Na,K-ATPase of canine renal medulla. Pharmacol Res 40:469-73
Karon, B S; Autry, J M; Shi, Y et al. (1999) Different anesthetic sensitivities of skeletal and cardiac isoforms of the Ca-ATPase. Biochemistry 38:9301-7
Shi, Y; Karon, B S; Kutchai, H et al. (1996) Phospholamban-dependent effects of C12E8 on calcium transport and molecular dynamics in cardiac sarcoplasmic reticulum. Biochemistry 35:13393-9
Mersol, J V; Kutchai, H; Mahaney, J E et al. (1995) Self-association accompanies inhibition of Ca-ATPase by thapsigargin. Biophys J 68:208-15
Karon, B S; Geddis, L M; Kutchai, H et al. (1995) Anesthetics alter the physical and functional properties of the Ca-ATPase in cardiac sarcoplasmic reticulum. Biophys J 68:936-45
Kutchai, H; Mahaney, J E; Geddis, L M et al. (1994) Hexanol and lidocaine affect the oligomeric state of the Ca-ATPase of sarcoplasmic reticulum. Biochemistry 33:13208-22