Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052329-02
Application #
2191309
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1995-09-30
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201

  Publications

Marcoux, Julien; Politis, Argyris; Rinehart, Dennis et al. (2014) Mass spectrometry defines the C-terminal dimerization domain and enables modeling of the structure of full-length OmpA. Structure 22:781-90
Zhuang, Tiandi; Tamm, Lukas K (2014) Control of the conductance of engineered protein nanopores through concerted loop motions. Angew Chem Int Ed Engl 53:5897-902
Buchanan, Kyle D; Huang, Shao-Ling; Kim, Hyunggun et al. (2010) Encapsulation of NF-kappaB decoy oligonucleotides within echogenic liposomes and ultrasound-triggered release. J Control Release 141:193-8
Lei, Guohua; MacDonald, Robert C (2008) Effects on interactions of oppositely charged phospholipid vesicles of covalent attachment of polyethylene glycol oligomers to their surfaces: adhesion, hemifusion, full fusion and ""endocytosis"". J Membr Biol 221:97-106
Koynova, Rumiana; Wang, Li; Macdonald, Robert C (2008) Cationic phospholipids forming cubic phases: lipoplex structure and transfection efficiency. Mol Pharm 5:739-44
Koynova, Rumiana; Wang, Li; MacDonald, Robert C (2007) Synergy in lipofection by cationic lipid mixtures: superior activity at the gel-liquid crystalline phase transition. J Phys Chem B 111:7786-95
Koynova, Rumiana; Macdonald, Robert C (2007) Natural lipid extracts and biomembrane-mimicking lipid compositions are disposed to form nonlamellar phases, and they release DNA from lipoplexes most efficiently. Biochim Biophys Acta 1768:2373-82
Koynova, Rumiana; Tarahovsky, Yury S; Wang, Li et al. (2007) Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim Biophys Acta 1768:375-86
Pozharski, Edwin V; MacDonald, Robert C (2007) Single lipoplex study of cationic lipoid-DNA, self-assembled complexes. Mol Pharm 4:962-74
Wang, Li; MacDonald, Robert C (2007) Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm 4:615-23

Showing the most recent 10 out of 40 publications