Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052540-02
Application #
2191607
Study Section
Special Emphasis Panel (ZRG2-HED-2 (01))
Project Start
1995-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cold Spring Harbor Laboratory
Department
Type
DUNS #
065968786
City
Cold Spring Harbor
State
NY
Country
United States
Zip Code
11724
Hoeppner, Daniel J; Spector, Mona S; Ratliff, Thomas M et al. (2004) eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans. Dev Biol 274:125-38
Degtyareva, Natasha P; Greenwell, Patricia; Hofmann, E Randal et al. (2002) Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. Proc Natl Acad Sci U S A 99:2158-63
Hofmann, E Randal; Milstein, Stuart; Boulton, Simon J et al. (2002) Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis. Curr Biol 12:1908-18
Villanueva, A; Lozano, J; Morales, A et al. (2001) jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans. EMBO J 20:5114-28
Gumienny, T L; Brugnera, E; Tosello-Trampont, A C et al. (2001) CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell 107:27-41
Ahmed, S; Alpi, A; Hengartner, M O et al. (2001) C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein. Curr Biol 11:1934-44
Gartner, A; Milstein, S; Ahmed, S et al. (2000) A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans. Mol Cell 5:435-43
Chung, S; Gumienny, T L; Hengartner, M O et al. (2000) A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans. Nat Cell Biol 2:931-7
Hengartner, M O (1999) Programmed cell death in the nematode C. elegans. Recent Prog Horm Res 54:213-22;discussion 222-4
Fraser, A G; James, C; Evan, G I et al. (1999) Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis. Curr Biol 9:292-301

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