Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052735-06
Application #
2191870
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1994-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
La Jolla Institute
Department
Type
DUNS #
603880287
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Follis, Ariele Viacava; Llambi, Fabien; Kalkavan, Halime et al. (2018) Regulation of apoptosis by an intrinsically disordered region of Bcl-xL. Nat Chem Biol 14:458-465
Follis, Ariele Viacava; Llambi, Fabien; Merritt, Parker et al. (2015) Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis. Mol Cell 59:677-84
Caro-Maldonado, Alfredo; Wang, Ruoning; Nichols, Amanda G et al. (2014) Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol 192:3626-36
Follis, Ariele Viacava; Llambi, Fabien; Ou, Li et al. (2014) The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat Struct Mol Biol 21:535-43
Follis, Ariele Viacava; Chipuk, Jerry E; Fisher, John C et al. (2013) PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis. Nat Chem Biol 9:163-8
Moldoveanu, Tudor; Grace, Christy R; Llambi, Fabien et al. (2013) BID-induced structural changes in BAK promote apoptosis. Nat Struct Mol Biol 20:589-97
Martinez, Jennifer; Verbist, Katherine; Wang, Ruoning et al. (2013) The relationship between metabolism and the autophagy machinery during the innate immune response. Cell Metab 17:895-900
Green, Douglas R; Rathmell, Jeffrey (2013) Sweet nothings: sensing of sugar metabolites controls T cell function. Cell Metab 18:7-8
Dillon, Christopher P; Oberst, Andrew; Weinlich, Ricardo et al. (2012) Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep 1:401-7
Wang, Ruoning; Green, Douglas R (2012) Metabolic checkpoints in activated T cells. Nat Immunol 13:907-15

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