Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM052896-01A1
Application #
2192095
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1996-05-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wayne State University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Belanger, Francois; Theberge-Julien, Gabriel; Cunningham, Philip R et al. (2005) A functional relationship between helix 1 and the 900 tetraloop of 16S ribosomal RNA within the bacterial ribosome. RNA 11:906-13
Laios, Eleftheria; Waddington, Marny; Saraiya, Ashesh A et al. (2004) Combinatorial genetic technology for the development of new anti-infectives. Arch Pathol Lab Med 128:1351-9
Belanger, Francois; Leger, Melissa; Saraiya, Ashesh A et al. (2002) Functional studies of the 900 tetraloop capping helix 27 of 16S ribosomal RNA. J Mol Biol 320:979-89
Chow, Christine S; Cunningham, Philip R; Lee, KangSeok et al. (2002) Photoinduced cleavage by a rhodium complex at G.U mismatches and exposed guanines in large and small RNAs. Biochimie 84:859-68
Morosyuk, S V; Cunningham, P R; SantaLucia Jr, J (2001) Structure and function of the conserved 690 hairpin in Escherichia coli 16 S ribosomal RNA. II. NMR solution structure. J Mol Biol 307:197-211
Lee, K; Holland-Staley, C A; Cunningham, P R (2001) Genetic approaches to studying protein synthesis: effects of mutations at Psi516 and A535 in Escherichia coli 16S rRNA. J Nutr 131:2994S-3004S
Morosyuk, S V; SantaLucia Jr, J; Cunningham, P R (2001) Structure and function of the conserved 690 hairpin in Escherichia coli 16 S ribosomal RNA. III. Functional analysis of the 690 loop. J Mol Biol 307:213-28
Holland-Staley, C A; Lee, K; Clark, D P et al. (2000) Aerobic activity of Escherichia coli alcohol dehydrogenase is determined by a single amino acid. J Bacteriol 182:6049-54
Morosyuk, S V; Lee, K; SantaLucia Jr, J et al. (2000) Structure and function of the conserved 690 hairpin in Escherichia coli 16 S ribosomal RNA: analysis of the stem nucleotides. J Mol Biol 300:113-26