Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM053069-01A1
Application #
2192330
Study Section
Special Emphasis Panel (ZRG3-BNP (02))
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Zhou, Lily; Wu, Jing; Janakiraman, Vijayalakshmi et al. (2012) Structure and characterization of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Aeropyrum pernix. Bioorg Chem 40:79-86
Yi, Li; Velasquez, Melvin S; Holler, Tod P et al. (2011) A simple assay for 3-deoxy-d-manno-octulosonate cytidylyltransferase and its use as a pathway screen. Anal Biochem 416:152-8
Wu, Jing; Woodard, Ronald W (2006) New insights into the evolutionary links relating to the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase subfamilies. J Biol Chem 281:4042-8
Wu, Jing; Sheflyan, Galina Ya; Woodard, Ronald W (2005) Bacillus subtilis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase revisited: resolution of two long-standing enigmas. Biochem J 390:583-90
Sundaram, Appavu K; Pitts, Lee; Muhammad, Kamilah et al. (2004) Characterization of N-acetylneuraminic acid synthase isoenzyme 1 from Campylobacter jejuni. Biochem J 383:83-9
Li, Jingjing; Wu, Jing; Fleischhacker, Angela S et al. (2004) Conversion of aquifex aeolicus 3-deoxy-d-manno-octulosonate 8-phosphate synthase, a metalloenzyme, into a nonmetalloenzyme. J Am Chem Soc 126:7448-9
Furdui, Cristina; Zhou, Lily; Woodard, Ronald W et al. (2004) Insights into the mechanism of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (Phe) from Escherichia coli using a transient kinetic analysis. J Biol Chem 279:45618-25
Woodard, Ronald W (2004) Unique biosynthesis of dehydroquinic acid? Bioorg Chem 32:309-15
Wu, Jing; Patel, Mayur A; Sundaram, Appavu K et al. (2004) Functional and biochemical characterization of a recombinant Arabidopsis thaliana 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Biochem J 381:185-93
Shumilin, Igor A; Bauerle, Ronald; Wu, Jing et al. (2004) Crystal structure of the reaction complex of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Thermotoga maritima refines the catalytic mechanism and indicates a new mechanism of allosteric regulation. J Mol Biol 341:455-66

Showing the most recent 10 out of 30 publications