Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM053146-02
Application #
2192429
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Seo, Hyuk-Soo; Kiel, Michael; Pan, Dongli et al. (2004) Kinetics and thermodynamics of RRF, EF-G, and thiostrepton interaction on the Escherichia coli ribosome. Biochemistry 43:12728-40
Druzina, Zhanna; Cooperman, Barry S (2004) Photolabile anticodon stem-loop analogs of tRNAPhe as probes of ribosomal structure and structural fluctuation at the decoding center. RNA 10:1550-62
Vanzi, Francesco; Vladimirov, Serguei; Knudsen, Charlotte R et al. (2003) Protein synthesis by single ribosomes. RNA 9:1174-9
Diedrich, G; Spahn, C M; Stelzl, U et al. (2000) Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer. EMBO J 19:5241-50
Wang, R; Alexander, R W; VanLoock, M et al. (1999) Three-dimensional placement of the conserved 530 loop of 16 S rRNA and of its neighboring components in the 30 S subunit. J Mol Biol 286:521-40
Bukhtiyarov, Y; Druzina, Z; Cooperman, B S (1999) Identification of 23S rRNA nucleotides neighboring the P-loop in the Escherichia coli 50S subunit. Nucleic Acids Res 27:4376-84