Molecular Basis and Function of Signal Transduction - Dianqing Wu

Abstract

Funding Agency

Agency: National Institute of Health (NIH)
Institute: National Institute of General Medical Sciences (NIGMS)
Type: Research Project (R01)
Project #: 1R01GM054597-01
Application #: 2193945
Study Section: Cellular Biology and Physiology Subcommittee 1 (CBY)

Project Start: 1996-07-01
Project End: 2000-06-30
Budget Start: 1996-07-01
Budget End: 1997-06-30
Support Year: 1
Fiscal Year: 1996
Total Cost
Indirect Cost

Institution

Name: University of Rochester
Department: Pharmacology
Type: Schools of Dentistry
DUNS #: 208469486

City: Rochester
State: NY
Country: United States
Zip Code: 14627

Related projects


NIH 2004 R01 GM	Molecular Function of Chemoattractant-Mediated Signaling Wu, Dianqing / University of Connecticut	$290,000
NIH 2003 R01 GM	Molecular Function of Chemoattractant-Mediated Signaling Wu, Dianqing / University of Connecticut	$289,280
NIH 2002 R01 GM	Molecular Function of Chemoattractant-Mediated Signaling Wu, Dianqing / University of Connecticut	$287,352
NIH 2001 R01 GM	Molecular Function of Chemoattractant-Mediated Signaling Wu, Dianqing / University of Connecticut	$282,720
NIH 2000 R01 GM	Molecular Basis and Function of Signal Transduction Wu, Dianqing / University of Connecticut	$64,244
NIH 1999 R01 GM	Molecular Basis and Function of Signal Transduction Wu, Dianqing / University of Rochester
NIH 1999 R01 GM	Molecular Basis and Function of Signal Transduction Wu, Dianqing / University of Connecticut
NIH 1998 R01 GM	Molecular Basis and Function of Signal Transduction Wu, Dianqing / University of Rochester
NIH 1997 R01 GM	Molecular Basis and Function of Signal Transduction Wu, Dianqing / University of Rochester
NIH 1996 R01 GM	Molecular Basis and Function of Signal Transduction Wu, Dianqing / University of Rochester

Publications

Gan, Xiaoqing; Wang, Jiyong; Wang, Chen et al. (2012) PRR5L degradation promotes mTORC2-mediated PKC-? phosphorylation and cell migration downstream of G?12. Nat Cell Biol 14:686-96

Qian, Feng; Le Breton, Guy C; Chen, Jia et al. (2012) Role for the guanine nucleotide exchange factor phosphatidylinositol-3,4,5-trisphosphate-dependent rac exchanger 1 in platelet secretion and aggregation. Arterioscler Thromb Vasc Biol 32:768-77

Greenfield, Edward M; Tatro, Joscelyn M; Smith, Matthew V et al. (2011) PI3K? deletion reduces variability in the in vivo osteolytic response induced by orthopaedic wear particles. J Orthop Res 29:1649-53

Xiao, Wenbin; Kashiwakura, Jun-Ichi; Hong, Hong et al. (2011) Phospholipase C-?3 regulates Fc?RI-mediated mast cell activation by recruiting the protein phosphatase SHP-1. Immunity 34:893-904

Tang, Wenwen; Zhang, Yong; Xu, Wenwen et al. (2011) A PLC?/PI3K?-GSK3 signaling pathway regulates cofilin phosphatase slingshot2 and neutrophil polarization and chemotaxis. Dev Cell 21:1038-50

Gan, Xiaoqing; Wang, Jiyong; Su, Bing et al. (2011) Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 286:10998-1002

Xu, Wenwen; Wang, Ping; Petri, Björn et al. (2010) Integrin-induced PIP5K1C kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration. Immunity 33:340-50

Zhang, Yong; Tang, Wenwen; Jones, Matthew C et al. (2010) Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils. J Biol Chem 285:24805-14

Colvin, Richard A; Means, Terry K; Diefenbach, Thomas J et al. (2010) Synaptotagmin-mediated vesicle fusion regulates cell migration. Nat Immunol 11:495-502

Shirakawa, Aiko-Konno; Liao, Fang; Zhang, Hongwei H et al. (2010) Pathway-selective suppression of chemokine receptor signaling in B cells by LPS through downregulation of PLC-?2. Cell Mol Immunol 7:428-39

Showing the most recent 10 out of 19 publications

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