Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054781-01
Application #
2194110
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1996-09-01
Project End
1997-06-30
Budget Start
1996-09-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Okitsu, Cindy Yen; Hsieh, Chih-Lin (2007) DNA methylation dictates histone H3K4 methylation. Mol Cell Biol 27:2746-57
Irvine, Ryan A; Lin, Iping G; Hsieh, Chih-Lin (2002) DNA methylation has a local effect on transcription and histone acetylation. Mol Cell Biol 22:6689-96
Lin, Iping G; Han, Li; Taghva, Alexander et al. (2002) Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro. Mol Cell Biol 22:704-23
Lin, I G; Hsieh, C L (2001) Chromosomal DNA demethylation specified by protein binding. EMBO Rep 2:108-12
Lin, I G; Tomzynski, T J; Ou, Q et al. (2000) Modulation of DNA binding protein affinity directly affects target site demethylation. Mol Cell Biol 20:2343-9
Hsieh, C L (1999) In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3b. Mol Cell Biol 19:8211-8
Hsieh, C L (1999) Evidence that protein binding specifies sites of DNA demethylation. Mol Cell Biol 19:46-56
Gauss, G H; Domain, I; Hsieh, C L et al. (1998) V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability. Eur J Immunol 28:351-8
Hsieh, C L (1997) Stability of patch methylation and its impact in regions of transcriptional initiation and elongation. Mol Cell Biol 17:5897-904