Structural Studies of Annexin Xii - Membrane Interaction

Luecke, Hartmut

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM056445-04
• Application #: 6138577
• Study Section: Biophysical Chemistry Study Section (BBCB)
• Program Officer: Lewis, Catherine D
• Project Start: 1997-01-01
• Project End: 2003-05-31
• Budget Start: 2000-01-01
• Budget End: 2003-05-31
• Support Year: 4
• Fiscal Year: 2000
• Total Cost: $138,499

Institution

• Name: University of California Irvine
• Department: Biochemistry
• Type: Schools of Arts and Sciences
• DUNS #: 161202122
• City: Irvine
• State: CA
• Country: United States
• Zip Code: 92697

Publications

Pathuri, Puja; Vogeley, Lutz; Luecke, Hartmut (2008) Crystal structure of metastasis-associated protein S100A4 in the active calcium-bound form. J Mol Biol 383:62-77

Luecke, Hartmut; Schobert, Brigitte; Stagno, Jason et al. (2008) Crystallographic structure of xanthorhodopsin, the light-driven proton pump with a dual chromophore. Proc Natl Acad Sci U S A 105:16561-5

Pathuri, Puja; Nguyen, Emily Tam; Svard, Staffan G et al. (2007) Apo and calcium-bound crystal structures of Alpha-11 giardin, an unusual annexin from Giardia lamblia. J Mol Biol 368:493-508

Stagno, Jason; Aphasizheva, Inna; Aphasizhev, Ruslan et al. (2007) Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc Natl Acad Sci U S A 104:14634-9

Stagno, Jason; Aphasizheva, Inna; Rosengarth, Anja et al. (2007) UTP-bound and Apo structures of a minimal RNA uridylyltransferase. J Mol Biol 366:882-99

Trakhanov, Sergei; Vyas, Nand K; Luecke, Hartmut et al. (2005) Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity. Biochemistry 44:6597-608

Freites, J Alfredo; Ali, Shahla; Rosengarth, Anja et al. (2004) Annexin A1 interaction with a zwitterionic phospholipid monolayer: a fluorescence microscopy study. Langmuir 20:11674-83

Rosengarth, Anja; Luecke, Hartmut (2003) A calcium-driven conformational switch of the N-terminal and core domains of annexin A1. J Mol Biol 326:1317-25

Prosise, Glen L; Luecke, Hartmut (2003) Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism. J Mol Biol 326:517-27

Tran, Jacqueline T; Rosengarth, Anja; Luecke, Hartmut (2002) Cloning, purification and crystallization of full-length human annexin 2. Acta Crystallogr D Biol Crystallogr 58:1854-7