The goals of the MBRS-RISE program at Fast Central University (ECU) are to encourage and motivate the high number of minority students from Oklahoma to complete a B.S. degree in Biology/Chemistry/Environmental Health Science, continue a graduate degree in the biomedical sciences, and pursue a career in biomedical research.
The specific aims of the ECU program include recruiting minority students from ECU finishing their sophomore year and students finishing 2-year colleges in the east central region of Oklahoma. The NIH-Bridges to the Baccalaureate program at ECU (renewed until 2001) has developed a consortium with Murray State College, Seminole State College, and Eastern Oklahoma State College, two-year state supported institutions. The students involved in the NIH-Bridges program will be a primary target for recruitment and will transition into the MBRS- RISE program at ECU. The students will attend colloquia at the ECU campus and visit research laboratories in Oklahoma. The speakers will be from various areas of the biomedical field and speak on their own research and career opportunities. Those students who are accepted into the MBRS-RISE at ECU will attend a summa workshop in which they will learn research techniques applicable to the biomedical field. The following Fall semester the students will attend a 4-year university and work part-time in the laboratory of a professor involved in the biomedical field. The students will also attend scientific meetings and visit other research laboratories. In the summer, each student will conduct an internship at a major research laboratory in the United States. At the end of the summer, each student will present their research project in a poster session at ECU and possibly, at other scientific meetings. The cycle would begin again each year with a new group of students. The MBRS-RISE at ECU will also assist in faculty development at ECU and the cooperating 2-year institutions by providing funding for faculty to conduct research during the school year and in the summer break, encourage faculty to attend scientific meetings, and seek to create avenues to enhance research opportunities for themselves and their students. At least 15 faculty members and 48 students from the cooperating institutions will participate in this program over a 4-year period.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM059996-02
Application #
6181543
Study Section
Metallobiochemistry Study Section (BMT)
Program Officer
Edmonds, Charles G
Project Start
1999-09-01
Project End
2003-08-31
Budget Start
2000-09-01
Budget End
2001-08-31
Support Year
2
Fiscal Year
2000
Total Cost
$198,927
Indirect Cost
Name
Purdue University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Mirzaei, Hamid; Regnier, Fred (2008) Protein:protein aggregation induced by protein oxidation. J Chromatogr B Analyt Technol Biomed Life Sci 873:8-14
Mirzaei, Hamid; Baena, Beatriz; Barbas, Coral et al. (2008) Identification of oxidized proteins in rat plasma using avidin chromatography and tandem mass spectrometry. Proteomics 8:1516-27
Regnier, Fred E (2007) An isotope coding strategy for proteomics involving both amine and carboxyl group labeling. Methods Mol Biol 359:125-33
Qiu, Ruiqing; Zhang, Xiang; Regnier, Fred E (2007) A method for the identification of glycoproteins from human serum by a combination of lectin affinity chromatography along with anion exchange and Cu-IMAC selection of tryptic peptides. J Chromatogr B Analyt Technol Biomed Life Sci 845:143-50
Mirzaei, Hamid; Regnier, Fred (2007) Identification of yeast oxidized proteins: chromatographic top-down approach for identification of carbonylated, fragmented and cross-linked proteins in yeast. J Chromatogr A 1141:22-31
Mirzaei, Hamid; Regnier, Fred (2006) Enrichment of carbonylated peptides using Girard P reagent and strong cation exchange chromatography. Anal Chem 78:770-8
Durham, Malaika; Regnier, Fred E (2006) Targeted glycoproteomics: serial lectin affinity chromatography in the selection of O-glycosylation sites on proteins from the human blood proteome. J Chromatogr A 1132:165-73
Mirzaei, Hamid; Schieler, Jeremy L; Rochet, Jean-Christophe et al. (2006) Identification of rotenone-induced modifications in alpha-synuclein using affinity pull-down and tandem mass spectrometry. Anal Chem 78:2422-31
Riggs, Larry; Seeley, Erin H; Regnier, Fred E (2005) Quantification of phosphoproteins with global internal standard technology. J Chromatogr B Analyt Technol Biomed Life Sci 817:89-96
Seeley, Erin H; Riggs, Larry D; Regnier, Fred E (2005) Reduction of non-specific binding in Ga(III) immobilized metal affinity chromatography for phosphopeptides by using endoproteinase glu-C as the digestive enzyme. J Chromatogr B Analyt Technol Biomed Life Sci 817:81-8

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