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Kim, Kyung Bo; Crews, Craig M (2013) From epoxomicin to carfilzomib: chemistry, biology, and medical outcomes. Nat Prod Rep 30:600-4
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Tae, Hyun Seop; Hines, John; Schneekloth, Ashley R et al. (2011) Unexpected stereochemical tolerance for the biological activity of tyroscherin. Bioorg Med Chem 19:1708-13
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Tae, Hyun Seop; Hines, John; Schneekloth, Ashley R et al. (2010) Total synthesis and biological evaluation of tyroscherin. Org Lett 12:4308-11
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Custar, Daniel W; Zabawa, Thomas P; Hines, John et al. (2009) Total synthesis and structure-activity investigation of the marine natural product neopeltolide. J Am Chem Soc 131:12406-14
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Kim, Kyung Bo; Crews, Craig M (2008) Chemical genetics: exploring the role of the proteasome in cell biology using natural products and other small molecule proteasome inhibitors. J Med Chem 51:2600-5
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Hines, John; Groll, Michael; Fahnestock, Margaret et al. (2008) Proteasome inhibition by fellutamide B induces nerve growth factor synthesis. Chem Biol 15:501-12
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Petri, Andreas F; Schneekloth Jr, John S; Mandal, Amit K et al. (2007) Synthesis of the C3-C18 fragment of amphidinolides G and H. Org Lett 9:3001-4
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Corson, Timothy W; Crews, Craig M (2007) Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell 130:769-74
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Hines, John; Roy, Myriam; Cheng, Hua et al. (2006) Myriaporone 3/4 structure--activity relationship studies define a pharmacophore targeting eukaryotic protein synthesis. Mol Biosyst 2:371-9
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Schneekloth Jr, John S; Sanders, John L; Hines, John et al. (2006) Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog. Bioorg Med Chem Lett 16:3855-8
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Showing the most recent 10 out of 31 publications
