Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM064662-02
Application #
6693366
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Program Officer
Chin, Jean
Project Start
2003-01-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$200,048
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Vertommen, Didier; Depuydt, Matthieu; Pan, Jonathan et al. (2008) The disulphide isomerase DsbC cooperates with the oxidase DsbA in a DsbD-independent manner. Mol Microbiol 67:336-49
Gleiter, Stefan; Bardwell, James C A (2008) Disulfide bond isomerization in prokaryotes. Biochim Biophys Acta 1783:530-4
Pan, Jonathan L; Sliskovic, Inga; Bardwell, James C A (2008) Mutants in DsbB that appear to redirect oxidation through the disulfide isomerization pathway. J Mol Biol 377:1433-42
Hiniker, Annie; Vertommen, Didier; Bardwell, James C A et al. (2006) Evidence for conformational changes within DsbD: possible role for membrane-embedded proline residues. J Bacteriol 188:7317-20
Hiniker, Annie; Collet, Jean-Francois; Bardwell, James C A (2005) Copper stress causes an in vivo requirement for the Escherichia coli disulfide isomerase DsbC. J Biol Chem 280:33785-91
Hiniker, Annie; Bardwell, James C A (2004) Disulfide relays between and within proteins: the Ero1p structure. Trends Biochem Sci 29:516-9
Masip, Lluis; Pan, Jonathan L; Haldar, Suranjana et al. (2004) An engineered pathway for the formation of protein disulfide bonds. Science 303:1185-9
Collet, Jean-Francois; D'Souza, Jonathan Conrad; Jakob, Ursula et al. (2003) Thioredoxin 2, an oxidative stress-induced protein, contains a high affinity zinc binding site. J Biol Chem 278:45325-32