Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM067230-02
Application #
6693772
Study Section
Special Emphasis Panel (ZRG1-SSS-U (01))
Program Officer
Deatherage, James F
Project Start
2003-01-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$388,096
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
781613492
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Roudot, Philippe; Liya Ding; Jaqaman, Khuloud et al. (2017) Piecewise-Stationary Motion Modeling and Iterative Smoothing to Track Heterogeneous Particle Motions in Dense Environments. IEEE Trans Image Process 26:5395-5410
Kwon, Mijung; Bagonis, Maria; Danuser, Gaudenz et al. (2015) Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds. Dev Cell 34:323-37
Loerke, Dinah; le Duc, Quint; Blonk, Iris et al. (2012) Quantitative imaging of epithelial cell scattering identifies specific inhibitors of cell motility and cell-cell dissociation. Sci Signal 5:rs5
Schaefer, Andrew W; Schoonderwoert, Vincent Th G; Ji, Lin et al. (2008) Coordination of actin filament and microtubule dynamics during neurite outgrowth. Dev Cell 15:146-62
Lim, Yangmi; Lim, Ssang-Taek; Tomar, Alok et al. (2008) PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. J Cell Biol 180:187-203
Delorme, Violaine; Machacek, Matthias; DerMardirossian, Celine et al. (2007) Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks. Dev Cell 13:646-62
Gupton, Stephanie L; Eisenmann, Kathryn; Alberts, Arthur S et al. (2007) mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration. J Cell Sci 120:3475-87
Yam, Patricia T; Wilson, Cyrus A; Ji, Lin et al. (2007) Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility. J Cell Biol 178:1207-21
Burnette, Dylan T; Schaefer, Andrew W; Ji, Lin et al. (2007) Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones. Nat Cell Biol 9:1360-9
Yarar, Defne; Waterman-Storer, Clare M; Schmid, Sandra L (2007) SNX9 couples actin assembly to phosphoinositide signals and is required for membrane remodeling during endocytosis. Dev Cell 13:43-56

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