Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM109194-06S1
Application #
10135529
Study Section
Synthetic and Biological Chemistry B Study Section (SBCB)
Program Officer
Yang, Jiong
Project Start
2014-05-15
Project End
2022-05-31
Budget Start
2019-06-01
Budget End
2020-05-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
California Institute of Technology
Department
Type
Schools of Arts and Sciences
DUNS #
009584210
City
Pasadena
State
CA
Country
United States
Zip Code
91125

  Publications

Ahn, Jun Myun; Ratani, Tanvi S; Hannoun, Kareem I et al. (2017) Photoinduced, Copper-Catalyzed Alkylation of Amines: A Mechanistic Study of the Cross-Coupling of Carbazole with Alkyl Bromides. J Am Chem Soc 139:12716-12723
Ahn, Jun Myun; Peters, Jonas C; Fu, Gregory C (2017) Design of a Photoredox Catalyst that Enables the Direct Synthesis of Carbamate-Protected Primary Amines via Photoinduced, Copper-Catalyzed N-Alkylation Reactions of Unactivated Secondary Halides. J Am Chem Soc 139:18101-18106
Zhao, Wei; Wurz, Ryan P; Peters, Jonas C et al. (2017) Photoinduced, Copper-Catalyzed Decarboxylative C-N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement. J Am Chem Soc 139:12153-12156
Matier, Carson D; Schwaben, Jonas; Peters, Jonas C et al. (2017) Copper-Catalyzed Alkylation of Aliphatic Amines Induced by Visible Light. J Am Chem Soc 139:17707-17710
Fu, Gregory C (2017) Transition-Metal Catalysis of Nucleophilic Substitution Reactions: A Radical Alternative to SN1 and SN2 Processes. ACS Cent Sci 3:692-700
Kainz, Quirin M; Matier, Carson D; Bartoszewicz, Agnieszka et al. (2016) Asymmetric copper-catalyzed C-N cross-couplings induced by visible light. Science 351:681-4
Johnson, Miles W; Hannoun, Kareem I; Tan, Yichen et al. (2016) A mechanistic investigation of the photoinduced, copper-mediated cross-coupling of an aryl thiol with an aryl halide. Chem Sci 7:4091-4100
Ratani, Tanvi S; Bachman, Shoshana; Fu, Gregory C et al. (2015) Photoinduced, Copper-Catalyzed Carbon-Carbon Bond Formation with Alkyl Electrophiles: Cyanation of Unactivated Secondary Alkyl Chlorides at Room Temperature. J Am Chem Soc 137:13902-7