The proposed study addresses the clinical question of the behavioral effects of iron deficiency anemia. Earlier studies have demonstrated that altered behavior and lower developmental test scores do not improve with iron therapy and that behavioral differences are still present at school entry. Building on the research team's previous work in Costa Rica and Guatemala, this study seeks to further characterize specific behavioral alterations among iron deficient infants. The study has four specific aims: (1) to characterize specific behavioral alterations in iron deficient anemic infants; (2) to determine if iron deficiency anemia has different behavioral effects in the first versus the second year of life; (3) to determine if environmental stimulation plus iron therapy corrects the behavior of infants with iron deficiency anemia; and (4) to determine of therapeutic interventions are more effective in the first or the second year of life.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
2R01HD014122-10A1
Application #
3312488
Study Section
Human Development and Aging Subcommittee 3 (HUD)
Project Start
1980-09-01
Project End
1995-11-30
Budget Start
1991-02-15
Budget End
1991-11-30
Support Year
10
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
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Lozoff, B; Klein, N K; Nelson, E C et al. (1998) Behavior of infants with iron-deficiency anemia. Child Dev 69:24-36

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